Identification of early predictors for infected necrosis in acute pancreatitis

BMC Gastroenterology

Table 1 Characterization of the patient cohort

	Infected necrosis (n = 59)	Sterile necrosis (n = 30)	p-value^a
Mean age (± SD), years	59.37 (± 15.05)	55.97 (± 15.26)	0.318
Sex (male), n (%)	48 (81.4)	24 (80.0)	0.878
Median BMI (IQR)^b, kg/m²	26.00 (3.80)	25.00 (5.00)	0.271
Smoking, n (%)	23 (54.8)	11 (55.0)	0.986
Etiology of acute pancreatitis, n (%)
Alcohol	24 (40.7)	6 (20.0)	0.051
Biliary	15 (25.4)	12 (40.0)	0.157
Acute on chronic pancreatitis	2 (3.4)	5 (16.7)	0.028
Post ERCP	2 (3.)	1 (3.3)	0.989
Other, including idiopathic	16 (27.1)	6 (20.00)	0.462
Localization of necrosis, n (%)
Pancreatic head	31 (52.5)	11 (36.7)	0.156
Pancreatic body	35 (59.3)	16 (53.3)	0.589
Pancreatic tail	36 (61.0)	23 (76.7)	0.140
Peripancreatic	11 (18.6)	2 (6.7)	0.130
Prior antibiotic therapy	25 (42.4)	3 (10.0)	0.002
Median APACHE-2 Score (IQR)^c	10.00 (9.00)	5.00 (5.00)	0.001
Median Charlson Comorbidity Index (IQR)	4.00 (3.00)	2.00 (4.00)	0.099
Diabetes mellitus, n (%)	18 (30.5)	7 (23.3)	0.476
Exocrine insufficiency, n (%)	14 (23.7)	3 (10.0)	0.119

^aSignificant differences between groups were tested using two-tailed t-test for normally distributed continuous variables, Kruskal–Wallis test for non-normally distributed continuous variables, and χ²- test or Fisher’s exact test for categorical variables
^bInfected necrosis (n = 40), sterile necrosis (n = 23)
^cInfected necrosis (n = 50), sterile necrosis (n = 28)

ISSN: 1471-230X