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Table 1 Demographics and clinical data by treatment strategy at index cholecystitis

From: Surgery for acute cholecystitis in severely comorbid patients: a population-based study on acute cholecystitis

   Total Surgery NOM p
Conservative Drain
Total Total 1 634 (100%) 725 (44%) 815 (50%) 94 (6%)
Sex Male 857 (52%) 373 (51%) 426 (52%) 58 (62%) 0.17
  Female 777 (48%) 352 (49%) 389 (48%) 36 (38%)  
Age Mean (SD) 64.2 (± 17.1) 57.4 (± 15.1) 69.0 (± 17.0) 76.0 (± 11.3)  < 0.001
BMI Mean (SD) 28.5 (± 5.5) 28.9 (± 5.1) 28.3 (± 5.9) 27.0 (± 5.7) 0.003
  Missing 117 (7.2%) 39 (5.4%) 71 (8.7%) 7 (7.4%)  
Smoking No/previous 1 486 (91%) 661 (91%) 740 (91%) 85 (90%) 0.93
  Yes, current 148 (9%) 64 (9%) 75 (9%) 9 (10%)  
Year of diagnosis 2017 401 (25%) 157 (22%) 218 (27%) 26 (28%) 0.057
  2018 405 (25%) 171 (24%) 205 (25%) 29 (31%)  
  2019 394 (24%) 194 (27%) 180 (22%) 20 (21%)  
  2020 434 (27%) 203 (28%) 212 (26%) 19 (20%)  
ASA 1 300 (18%) 195 (27%) 100 (12%) 5 (5%)  < 0.001
  2 731 (45%) 375 (52%) 328 (40%) 28 (30%)  
  3 515 (32%) 152 (21%) 316 (39%) 47 (50%)  
  4 87 (5%) 2 (0%) 71 (9%) 14 (15%)  
  5 1 (0%) 1 (0%) 0 (0%) 0 (0%)  
CCI Mean (SD) 3.2 (± 2.6) 2.0 (± 1.9) 4.0 (± 2.8) 5.4 (± 2.7)  < 0.001
Cholecystitis Grade G1 798 (49%) 425 (59%) 338 (41%) 35 (37%)  < 0.001
  G2-3 729 (45%) 268 (37%) 402 (49%) 59 (63%)  
  Missing 107 (7%) 32 (4%) 75 (9%) 0 (0%)  
Length of stay Mean (SD) 4.7 (± 5.6) 4.1 (± 5.0) 4.6 (± 5.8) 9.4 (± 5.3)  < 0.001
  Missing 52 (3.2%) 0 (0%) 52 (6.4%) 0 (0%)  
Readmitted within 30 days No 1 445 (88%) 681 (94%) 692 (85%) 72 (77%)  < 0.001
  Yes 189 (12%) 44 (6%) 123 (15%) 22 (23%)  
30d Mortality Alive 1,481 (91%) 708 (98%) 694 (85%) 79 (84%)  < 0.001
  Dead 34 (2%) 2 (0%) 25 (3%) 7 (7%)  
  Missing 119 (7%) 15 (2%) 96 (12%) 8 (9%)  
1y mortality Alive 1,426 (87%) 704 (97%) 653 (80%) 69 (73%)  < 0.001
  Dead 89 (5%) 6 (1%) 66 (8%) 17 (18%)  
  Missing 119 (7%) 15 (2%) 96 (12%) 8 (9%)  
  1. Fisher Exact Test used for categorical variables. Kruskal-Wallis test for continuous variables
  2. ASA American Society of Anesthesiologists physical status classification, BMI Body Mass Index, CCI Charlson Comorbidity Index, NOM Non-operative management