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Table 2 Univariate and multivariate analyses of preoperative MR imaging findings in predicting MVI or Grade

From: Clinical and imaging features preoperative evaluation of histological grade and microvascular infiltration of hepatocellular carcinoma

 

Univariate analysis (MVI)

multivariate analyses (MVI)

Univariate analysis (grade)

multivariate analyses (grade)

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

P

Age

0.991 (0.963, 1.021)

0.571

  

1.022 ( 0.990, 0.055)

0.178

  

Sex

1.844 (0.812, 4.185)

0.143

  

0.520 (0.223, 1.210)

0.129

  

Lipid

1.191 (0.61, 2.327)

0.609

  

2.014 (0.917, 4.424)

0.081

2.551 (0.96, 6.78)

0.06

Tumor Size

2.154 (1.069, 4.338)

0.032

5.174 (1.625, 16.477)

0.005

1.011 (0.47, 2.175)

0.979

  

AFP(ref: > 0, ≤ 20)

 > 20, ≤ 400

2.139 (1.015, 4.508)

0.046

1.845 (0.729, 4.673)

0.196

2.513 (1.133, 5.574)

0.023

1.325 (0.529, 3.321)

0.548

 > 400

4.375 (1.888, 10.14)

0.001

2.554 (0.84, 7.765)

0.098

2.437 (0.951, 6.242)

0.063

2.553 (0.804, 8.114)

0.112

HBsAg

2.457 (0.877, 6.887)

0.087

4.373 (1.193, 16.029)

0.026

0.764 (0.287, 2.036)

0.591

  

HBeAg

1.135 (0.587, 2.194)

0.706

  

0.676 (0.339, 1.349)

0.267

  

Tumor Number

3.102 (1.386, 6.94)

0.006

4.79 (1.565, 14.661)

0.006

4.05 (1.168, 14.046)

0.027

5.948 (1.345, 26.298)

0.019

Cirrhosis

1.267 (0.614, 2.613)

0.522

  

0.311 (0.122, 0.791)

0.014

0.252 (0.088, 0.719)

0.010

Capsule

0.43 (0.21, 0.883)

0.022

0.293 (0.098, 0.877)

0.028

0.414 (0.208, 0.822)

0.012

0.289 (0.123, 0.68)

0.004

Arterial rim enhancement

2.892 (1.515, 5.523)

0.001

2.141 (0.945, 4.853)

0.068

1.294 (0.661, 2.532)

0.452

  

Arterial peritumoral enhancement

12.86 (4.129, 40.055)

 < 0.001

5.02 (1.219, 20.68)

0.026

0.67 (0.264, 1.699)

0.398

  

Tumor margin

3.712 (1.84, 7.485)

 < 0.001

4.12 (1.621, 10.474)

0.003

1.052 (0.538, 2.055)

0.883

  

Tumor hypointensity on HBP

0.498 (0.133, 1.857)

0.299

  

0.47 (0.154, 1.435)

0.185

  

Peritumoral hypointensity on HBP

5.889 (2.475, 14.01)

 < 0.001

1.898 (0.528, 6.829)

0.326

2.004 (0.717, 5.597)

0.185

  

Shape(ref: round)

Oval

0.952 (0.315, 2.879)

0.931

  

1.533 (0.515, 4.567)

0.443

3.08 (0.82, 11.572)

0.096

Lobulated

1.301 (0.614, 2.755)

0.492

  

3.226 (1.4, 7.435)

0.006

5.282 (1.962, 14.22)

0.001

Irregular

1.333 (0.539, 3.301)

0.534

  

1.971 (0.757, 5.136)

0.165

2.188 (0.71, 6.741)

0.173