Characteristic | Univariable analysis | Multivariable analysis | ||||
---|---|---|---|---|---|---|
HR | 95% CI | P value | HR | 95% CI | P value | |
Age | ||||||
<40 | Reference | Â | Â | Reference | Â | Â |
40–59 | 0.812 | 0.642–1.027 | 0.082 | 1.016 | 0.801–1.290 | 0.895 |
60–79 | 1.271 | 1.019–1.586 | 0.033 | 1.617 | 1.287–2.033 | < 0.001 |
≥80 | 2.580 | 2.059–3.232 | <0.001 | 3.000 | 2.361–3.813 | < 0.001 |
Sex | ||||||
Male | Reference | Â | Â | Reference | Â | Â |
Female | 0.880 | 0.810–0.957 | 0.003 | 0.816 | 0.746–0.892 | < 0.001 |
Race | ||||||
White | Reference | Â | Â | Reference | Â | Â |
Black | 1.137 | 0.993–1.302 | 0.063 | – | – | – |
Other | 1.059 | 0.926–1.211 | 0.404 | – | – | – |
Marital status | ||||||
Married | Reference | Â | Â | Reference | Â | Â |
Separated/Divorced | 1.174 | 1.010–1.364 | 0.037 | 1.254 | 1.078–1.458 | 0.003 |
Widowed | 1.960 | 1.771–2.169 | < 0.001 | 1.581 | 1.407–1.776 | < 0.001 |
Single | 1.360 | 1.207–1.531 | < 0.001 | 1.483 | 1.311–1.677 | < 0.001 |
Primary tumor sites | ||||||
Cardiac/Fundus | Reference | Â | Â | Reference | Â | Â |
Body | 0.999 | 0.843–1.184 | 0.991 | 1.171 | 0.986–1.389 | 0.072 |
Antrum/Pylorus | 0.994 | 0.804–1.108 | 0.481 | 1.022 | 0.870–1.200 | 0.793 |
Lesser/Greater curvature | 0.897 | 0.744–1.082 | 0.255 | 0.938 | 0.778–1.132 | 0.508 |
Other | 1.211 | 1.062–1.380 | 0.004 | 1.185 | 1.040–1.352 | 0.011 |
Histologic subtype | ||||||
DLBCL | Reference | Â | Â | Reference | Â | Â |
MALT | 0.238 | 0.214–0.265 | < 0.001 | 0.248 | 0.219–0.281 | < 0.001 |
Other B cell lymphoma | 1.047 | 0.900–1.218 | 1.047 | 0.848 | 0.727–0.990 | 0.036 |
T/NK cell lymphoma | 1.790 | 1.379–2.323 | < 0.001 | 1.762 | 1.355–2.291 | < 0.001 |
Other NHL | 0.932 | 0.775–1.121 | 0.455 | 0.867 | 0.720–1.045 | 0.134 |
HL | 1.516 | 0.757–3.038 | 0.240 | 1.198 | 0.595–2.410 | 0.613 |
NOS | 0.844 | 0.655–1.086 | 0.187 | 0.774 | 0.599–0.999 | 0.049 |
Stage | ||||||
stage I | Reference | Â | Â | Reference | Â | Â |
stage II | 1.845 | 1.643–2.072 | < 0.001 | 1.588 | 1.407–1.793 | < 0.001 |
stage III | 2.548 | 2.183–2.974 | < 0.001 | 1.991 | 1.695–2.339 | < 0.001 |
stage IV | 3.305 | 2.999–3.644 | < 0.001 | 2.551 | 2.294–2.838 | < 0.001 |
Surgery | ||||||
Yes | Reference | Â | Â | Reference | Â | Â |
No/Unknown | 0.866 | 0.762–0.985 | 0.028 | 1.063 | 0.931–1.214 | 0.368 |
Radiotherapy | ||||||
Yes | Reference | Â | Â | Reference | Â | Â |
No/Unknown | 1.833 | 1.642–2.047 | < 0.001 | 1.209 | 1.079–1.354 | 0.001 |
Chemotherapy | ||||||
Yes | Reference | Â | Â | Reference | Â | Â |
No/Unknown | 0.608 | 0.559–0.662 | < 0.001 | 1.491 | 1.346–1.652 | < 0.001 |