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Table 3 Cox proportional hazard regression analysis of CSS in patients with primary gastric lymphoma in the training cohort (n=8898)

From: A dynamic predictive nomogram of long-term survival in primary gastric lymphoma: a retrospective study

Characteristic

Univariable analysis

Multivariable analysis

HR

95% CI

P value

HR

95% CI

P value

Age

<40

Reference

  

Reference

  

40–59

0.812

0.642–1.027

0.082

1.016

0.801–1.290

0.895

60–79

1.271

1.019–1.586

0.033

1.617

1.287–2.033

< 0.001

≥80

2.580

2.059–3.232

<0.001

3.000

2.361–3.813

< 0.001

Sex

Male

Reference

  

Reference

  

Female

0.880

0.810–0.957

0.003

0.816

0.746–0.892

< 0.001

Race

White

Reference

  

Reference

  

Black

1.137

0.993–1.302

0.063

–

–

–

Other

1.059

0.926–1.211

0.404

–

–

–

Marital status

Married

Reference

  

Reference

  

Separated/Divorced

1.174

1.010–1.364

0.037

1.254

1.078–1.458

0.003

Widowed

1.960

1.771–2.169

< 0.001

1.581

1.407–1.776

< 0.001

Single

1.360

1.207–1.531

< 0.001

1.483

1.311–1.677

< 0.001

Primary tumor sites

Cardiac/Fundus

Reference

  

Reference

  

Body

0.999

0.843–1.184

0.991

1.171

0.986–1.389

0.072

Antrum/Pylorus

0.994

0.804–1.108

0.481

1.022

0.870–1.200

0.793

Lesser/Greater curvature

0.897

0.744–1.082

0.255

0.938

0.778–1.132

0.508

Other

1.211

1.062–1.380

0.004

1.185

1.040–1.352

0.011

Histologic subtype

DLBCL

Reference

  

Reference

  

MALT

0.238

0.214–0.265

< 0.001

0.248

0.219–0.281

< 0.001

Other B cell lymphoma

1.047

0.900–1.218

1.047

0.848

0.727–0.990

0.036

T/NK cell lymphoma

1.790

1.379–2.323

< 0.001

1.762

1.355–2.291

< 0.001

Other NHL

0.932

0.775–1.121

0.455

0.867

0.720–1.045

0.134

HL

1.516

0.757–3.038

0.240

1.198

0.595–2.410

0.613

NOS

0.844

0.655–1.086

0.187

0.774

0.599–0.999

0.049

Stage

stage I

Reference

  

Reference

  

stage II

1.845

1.643–2.072

< 0.001

1.588

1.407–1.793

< 0.001

stage III

2.548

2.183–2.974

< 0.001

1.991

1.695–2.339

< 0.001

stage IV

3.305

2.999–3.644

< 0.001

2.551

2.294–2.838

< 0.001

Surgery

Yes

Reference

  

Reference

  

No/Unknown

0.866

0.762–0.985

0.028

1.063

0.931–1.214

0.368

Radiotherapy

Yes

Reference

  

Reference

  

No/Unknown

1.833

1.642–2.047

< 0.001

1.209

1.079–1.354

0.001

Chemotherapy

Yes

Reference

  

Reference

  

No/Unknown

0.608

0.559–0.662

< 0.001

1.491

1.346–1.652

< 0.001

  1. The bold numbers indicate that the variables have statistical differences (P < 0.05)