Fig. 2

The expression of therapy-related proteins in the gastric tumors. A Strong and diffuse positive for EGFR in SCC (Triangle; magnification, ×100, scale bar: 100 μm), but weak to moderately positive in AC (arrow; magnification, ×100, scale bar: 100 μm) and GCLS (inset, magnification, ×400, scale bar: 20 μm). B Immunohistochemical score for HER2 expression is 1 + in SCC (magnification, ×100, scale bar: 100 μm) and GCLS (inset, magnification, ×400, scale bar: 20 μm). C p53 staining is patchy positive in SCC (magnification, ×100, scale bar: 100 μm; inset, magnification, ×400, scale bar: 20 μm). D Positive expression for PD-L1 on lymphocytes in and around SCC (magnification, ×100, scale bar: 100 μm) and GCLS (inset, magnification, ×400, scale bar: 20 μm). The combined positive score for PD-L1 expression is 15 (CPS = 15)