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Table 2 SF-36 mean scores for each group before and after treatment. BAD: bile acid diarrhoea, PC: post-cholecystectomy, CD: terminal ileal resected Crohn’s Disease

From: The impact of treatment with bile acid sequestrants on quality of life in patients with bile acid diarrhoea

Field

Time

Control Group

BAD

PC

CD

p Value

Physical Functioning (PF)

Before

66.00

(52.78–79.23)

75.17

(63.18–87.15)

63.66

(42.97–84.34)

75.00

(55.26–94.74

0.60

After

 

78.00

(66.63–89.37)

62.17

(42.87–81.47)

80.50

(65.19–95.81)

0.17

p value

p = 0.27

p = 0.79

p = 0.32

 

Role limitation due to physical health (RP)

Before

41.35

(23.75–59.94)

32.89

(13.61–52.18)

54.17

(26.38–81.96)

52.50

(19.36–85.64)

0.50

After

 

53.95

(34.57–73.32)

35.42

(4.78–66.05)

52.50

(18.31–86.69)

0.50

p value

*p = 0.02

p = 0.11

p = 1.00

 

Bodily Pain (BP)

Before

52.60

(41.55–63.64)

47.5

(35.12–59.88)

46.46

(37.46–55.46)

57.50

(32.85–82.15)

0.71

After

 

57.78

(45.53–70.02)

46.04

(26.25–65.83)

67.5

(50.89–84.11)

0.18

p value

P = 0.13

P = 0.96

P = 0.33

 

General Health (GH)

Before

44.60

(34.23–54.97)

43.47

(29.54–57.40)

45.42

(33.73–57.11)

40.00

(20.78–59.22)

0.96

After

 

43.89

(33.85–53.93)

47.08

(31.03–63.14)

46.50

(28.26–64.74)

0.92

p value

p = 0.92

p = 0.70

p = 0.11

 

Vitality (VT)

Before

39.40

(29.60–49.20)

30.25

(18.04–42.46)

40.68

(27.80–53.56)

23.50

(11.22–35.78)

0.19

After

 

38.5

(26.88–50.12)

37.27

(19.35–55.19)

30.50

(11.84–49.16)

0.72

p value

p = 0.11

p = 0.61

p = 0.25

 

Social Functioning (SF)

Before

69.79

(57.64–81.94)

56.75

(42.20–71.30)

67.71

(52.77–82.65)

58.75

(41.86–75.64)

0.41

After

 

65.63

(52.63–78.62)

66.67

(48.33–85.01)

66.25

(47.38–85.12)

0.99

p value

p = 0.11

p = 0.90

p = 0.11

 

Role limitation due to emotional health (RE)

Before

58.67

(40.34–76.99)

45.00

(25.88–64.12)

52.78

(25.00–80.55)

53.33

(21.14–85.52)

0.78

After

 

65.00

(45.74–84.26)

44.44

(14.04–74.85)

66.67

(36.93–96.41)

0.37

p value

p = 0.08

p = 0.63

p = 0.17

 

Emotional well-being (EB)

Before

64.96

(54.99–74.93)

56.13

(45.96–66.30)

59.33

(47.29–71.38)

60.80

(49.86–71.74)

0.56

After

 

62.67

(52.39–72.14)

61.61

(43.58–79.64)

70.00

(56.90–83.10)

0.63

p value

p = 0.27

p = 0.68

p = 0.15

 

Physical component summary (PCS)

Before

51.20

(44.57–57.83)

50.21

(42.44–57.97)

52.42

(43.83–61.02)

56.79

(45.13–68.46)

0.94

After

 

58.87

(51.82–65.91)

47.68

(37.50–57.86)

61.86

(51.03–72.69)

0.37

p value

p = 0.15

p = 0.37

p = 0.26

 

Mental component summary (MCS)

Before

58.09

(51.50–64.68)

47.03

(39.90–54.17)

55.43

(46.86–64.00)

49.10

(39.24–58.95)

0.46

After

 

57.85

(50.90–64.80)

52.82

(42.48–63.16)

58.35

(47.94–68.77)

0.83

p value

* p = 0.03

p = 0.73

p = 0.07

 
  1. 95% CI is represented within parenthesis. The p values in the far-right column reflect group comparisons before treatment and after treatment respectively. * denotes p < 0.05