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Table 1 Comparison of patient groups who did and did not have an improvement in their quality of life pre and post treatment

From: The impact of treatment with bile acid sequestrants on quality of life in patients with bile acid diarrhoea

 

Grade of Effect size

Group

p Value

SF-36

 Physical component

Small

BAD

0.15

Small

PC

0.37

Small

CD

0.26

 Mental component

Moderate

BAD

*0.03

Null

PC

0.73

Moderate

CD

0.07

EQ-5D-3L

 Mobility

Null

BAD

1.00

Small

PC

0.34

Small

CD

0.17

 Self-care

Small

BAD

0.33

Small

PC

0.34

Small

CD

0.34

 Activity

Moderate

BAD

*0.002

Small

PC

0.44

Null

CD

1.00

 Pain & Discomfort

Small

BAD

0.16

Null

PC

0.59

Moderate

CD

0.10

 Anxiety & Depression

Small

BAD

0.06

Small

PC

0.19

Small

CD

0.19

 VAS

Null

BAD

0.48

Small

PC

0.39

Small

CD

0.26

 IBDQ-32

Moderate

CD

*0.03

  1. Effect size was calculated by dividing the difference between baseline and post-treatment scores by the standard deviation of baseline scores, where effect sizes of > 0.2 was considered small, > 0.5 moderate and > 0.8 large. Null effect sizes are those who did not achieve any improvement in their quality of life scores. * denotes p < 0.05