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Table 2 Distributions of LRP5 rs556442 genotypes and allele frequencies in the four groupsa

From: Association between the LRP5 rs556442 gene polymorphism and the risks of NAFLD and CHD in a Chinese Han population

 

NAFLD

CHD

NAFLD + CHD

Control

P1

P2

P3

P4

P5

P6

All NAFLD

Lean NAFLD

Obese NAFLD

Genotype frequency, n (%)

 AA

126 (51.01)

37 (50.00)

89 (51.45)

102 (51.00)

59 (50.00)

174 (51.33)

0.986

0.260

0.436

0.417

0.043

0.793

 AG

102 (41.30)

30 (40.54)

72 (41.62)

89 (44.50)

45 (38.14)

138 (40.71)

 GG

19 (7.69)

7 (9.46)

12 (6.93)

9 (4.50)

14 (11.86)

27 (7.96)

Allele frequency, n (%)

 A

354 (71.66)

104 (70.27)

250 (72.25)

150 (71.43)

163 (69.07)

486 (71.68)

0.994

0.578

0.446

0.471

0.258

0.654

 G

140 (28.34)

44 (29.73)

96 (27.74)

60 (28.57)

73 (30.93)

192 (28.32)

  1. NAFLD non-alcoholic fatty liver disease, CHD coronary heart disease
  2. P1: NAFLD patients vs. healthy controls; P2: CHD patients vs. healthy controls; P3: NAFLD + CHD patients vs. healthy controls; P4: NAFLD patients vs. NAFLD + CHD patients; P5: CHD patients vs. NAFLD + CHD patients; P6: lean NAFLD patients vs. obese NAFLD patients
  3. aData were compared by chi-square test