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Fig. 1 | BMC Gastroenterology

Fig. 1

From: Pancreatic involvement in Erdheim-Chester disease: a case report and review of the literature

Fig. 1

Imaging and pathological data at the time of diagnosis. a Histological examination of the sellar mass showed histiocytic aggregates(× 200, scale bar: 50 µM), which were CD1a-negative, Langerin-negative, and b S100-positive on immunohistochemistry (× 200, scale bar: 50 µM). c Enhanced brain MRI showed multiple lesions affecting sellar, suprasellar area, pons, and part of hypothalamus. d 99mTc-MDP bone scrintigraphy scan showed symmetrical increased uptake in the frontal bone and distal femoral and proximal tibial metaphysis. e HR-pQCT confirmed osteosclerosis by revealing increased trabecular volumetric bone mineral density and localized structural alteration of trabeculae network in tibia. f PET/CT revealed hypermetabolic foci in the bilateral frontal lobe, saddle area, and pancreas. g Enhanced abdominal CT scan showed nodules of hypointense lesions within the body and tail of the slightly enlarged pancreas. h EUS-FNA of pancreas found no evidence of malignancy but only normal pancreatic ductal cells (× 400, scale bar: 25 µM)

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