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Table 3 Gastrointestinal symptom details of patients with symptoms of gastroparesis who underwent gastric emptying scintigraphy

From: A cross-sectional study describing peripheral neuropathy in patients with symptoms of gastroparesis: associations with etiology, gastrointestinal symptoms, and gastric emptying

 

All (including DPSG)

Idiopathic

(n = 166)

(n = 99)

Delayed Emptying

Normal Emptying

 

Delayed Emptying

Normal Emptying

 

n = 85

n = 81

n = 43

n = 56

PN

nPN

PN

nPN

p value

PN

nPN

PN

nPN

p value

(n = 27)

(n = 58)

(n = 19)

(n = 62)

(n = 7)

(n = 36)

(n = 9)

(n = 47)

NTSS-6 score

11.40 ± 3.52

1.30 ± 1.94

9.50 ± 3.09

1.60 ± 2.01

 < 0.005*

11.09 ± 2.05

1.36 ± 1.87

10.33 ± 3.28

1.42 ± 1.91

 < 0.005*

Nausea

4.02 ± 1.06

3.45 ± 1.38

3.37 ± 1.34

3.28 ± 1.51

0.170

4.14 ± 1.21

3.58 ± 1.13

3.44 ± 1.24

3.18 ± 1.42

0.278

Retching

2.91 ± 1.72

2.45 ± 1.85

2.58 ± 1.43

1.90 ± 1.65

0.054

3.43 ± 2.37

2.56 ± 1.83

2.78 ± 1.48

1.83 ± 1.51

0.040*

Vomiting

3.31 ± 1.79

2.69 ± 1.84

2.42 ± 1.54

1.93 ± 1.86

0.006*

3.47 ± 1.87

2.53 ± 1.89

2.67 ± 1.80

1.87 ± 1.83

0.110

Stomach Fullness

3.78 ± 1.37

3.77 ± 1.12

3.79 ± 0.98

3.64 ± 1.12

0.802

4.29 ± 0.95

3.49 ± 1.20

3.67 ± 1.00

3.67 ± 1.02

0.402

Feeling excessively full

4.09 ± 1.24

3.77 ± 1.27

3.95 ± 1.13

3.65 ± 1.41

0.363

4.29 ± 1.11

3.53 ± 1.44

3.89 ± 1.27

3.63 ± 1.42

0.491

Not able to finish meal

3.59 ± 1.55

3.59 ± 1.41

3.82 ± 1.12

3.56 ± 1.48

0.979

3.29 ± 1.89

3.56 ± 1.50

3.78 ± 1.20

3.64 ± 1.37

0.983

Loss of appetite

3.67 ± 1.20

3.09 ± 1.57

3.79 ± 1.03

3.24 ± 1.71

0.316

3.14 ± 1.68

3.17 ± 1.50

4.11 ± 0.93

3.32 ± 1.64

0.410

Bloating

3.52 ± 1.50

3.32 ± 1.45

3.95 ± 1.13

3.11 ± 1.56

0.141

3.86 ± 1.77

3.26 ± 1.54

3.89 ± 0.78

3.02 ± 1.57

0.233

Abdominal distension

3.17 ± 1.75

2.88 ± 1.62

3.32 ± 1.67

2.47 ± 1.72

0.083

4.43 ± 0.53

2.89 ± 1.68

2.89 ± 1.90

2.26 ± 1.74

0.007*

Upper abdominal pain

3.41 ± 1.45

2.82 ± 1.83

3.26 ± 1.48

2.68 ± 1.78

0.318

4.14 ± 1.07

3.21 ± 1.65

3.33 ± 1.22

2.66 ± 1.80

0.118

Upper abd. discomfort

3.31 ± 1.48

2.86 ± 1.75

3.53 ± 1.12

3.02 ± 1.65

0.634

3.57 ± 1.90

3.37 ± 1.57

3.44 ± 1.01

2.91 ± 1.69

0.449

Lower abdominal pain

2.78 ± 1.67

1.81 ± 1.57

3.37 ± 1.22

1.95 ± 1.40

 < 0.005*

3.14 ± 1.86

2.14 ± 1.57

4.06 ± 0.73

1.91 ± 1.38

 < 0.005*

Lower abd. discomfort

2.89 ± 1.69

2.09 ± 1.62

3.61 ± 0.86

2.07 ± 1.40

 < 0.005*

3.14 ± 1.86

2.31 ± 1.47

4.06 ± 0.73

2.10 ± 1.37

0.001*

Heartburn during the day

2.15 ± 1.61

2.33 ± 1.68

2.00 ± 1.80

1.80 ± 1.69

0.361

1.71 ± 1.70

2.58 ± 1.59

2.56 ± 2.07

1.84 ± 1.57

0.142

Recumbent heartburn

2.22 ± 1.72

2.38 ± 1.74

1.68 ± 1.80

1.65 ± 1.72

0.086

1.57 ± 1.72

2.53 ± 1.61

2.00 ± 2.00

1.68 ± 1.63

0.118

Daytime chest discomfort

2.30 ± 1.41

1.60 ± 1.45

2.21 ± 1.51

1.66 ± 1.65

0.115

2.43 ± 1.13

1.66 ± 1.45

2.67 ± 1.73

1.64 ± 1.65

0.215

Recumbent chest discomfort

2.30 ± 1.56

1.59 ± 1.67

2.11 ± 1.24

1.46 ± 1.63

0.042*

2.29 ± 1.25

1.72 ± 1.73

2.44 ± 1.42

1.47 ± 1.60

0.213

Daytime reflux

2.74 ± 1.77

2.58 ± 1.67

2.37 ± 1.83

2.04 ± 1.82

0.277

4.00 ± 0.82

2.85 ± 1.66

3.67 ± 1.66

2.14 ± 1.77

0.009*

Nighttime reflux

2.59 ± 1.80

2.74 ± 1.78

2.32 ± 1.80

1.77 ± 1.70

0.178

3.57 ± 1.62

2.83 ± 1.72

3.44 ± 1.59

1.94 ± 1.70

0.006*

Bitter taste

2.63 ± 1.62

2.13 ± 1.68

2.21 ± 1.75

1.66 ± 1.63

0.073

3.57 ± 0.98

2.23 ± 1.67

3.00 ± 1.66

1.62 ± 1.62

0.007*

GCSI Total Score

3.51 ± 0.86

3.16 ± 0.97

3.42 ± 0.91

2.90 ± 1.00

0.034*

3.86 ± 0.83

3.12 ± 1.05

3.40 ± 0.98

2.83 ± 0.98

0.065

PAGI-SYM Total Score

3.19 ± 0.93

2.73 ± 0.96

3.21 ± 0.79

2.54 ± 0.93

0.003*

3.55 ± 0.98

2.84 ± 1.01

3.41 ± 0.73

2.50 ± 0.93

0.010*

 

Diabetic

Postsurgical

(n = 42)

(n = 21)

Delayed Emptying

Normal Emptying

 

Delayed Emptying

Normal Emptying

 

n = 22

n = 20

n = 16

n = 5

PN

nPN

PN

nPN

p value

PN

nPN

PN

nPN

p value

(n = 14)

(n = 8)

(n = 8)

(n = 12)

(n = 4)

(n = 12)

(n = 2)

(n = 3)

NTSS-6 score

11.68 ± 4.06

0.79 ± 1.53

9.24 ± 3.05

2.08 ± 2.27

 < 0.005*

9.90 ± 3.24

0.86 ± 2.01

6.83 ± 0.24

2.44 ± 2.69

0.001*

Nausea

4.11 ± 0.96

3.50 ± 1.41

3.25 ± 1.67

3.17 ± 1.75

0.452

4.00 ± 1.15

2.83 ± 1.95

3.50 ± 0.71

5.00 ± 0.00

0.159

Retching

2.91 ± 1.46

3.00 ± 1.93

2.38 ± 1.60

1.67 ± 1.83

0.248

2.00 ± 1.63

1.50 ± 1.73

2.50 ± 0.71

3.33 ± 2.08

0.369

Vomiting

3.57 ± 1.74

2.88 ± 1.89

2.50 ± 1.20

1.92 ± 1.88

0.071

2.75 ± 2.22

2.86 ± 1.79

1.00 ± 1.41

2.67 ± 2.52

0.611

Stomach Fullness

3.50 ± 1.65

4.13 ± 0.64

3.63 ± 0.92

3.17 ± 1.34

0.377

4.25 ± 0.96

4.17 ± 0.94

5.00 ± 0.00

4.67 ± 0.58

0.553

Feeling excessively full

4.04 ± 1.42

3.88 ± 0.83

3.75 ± 1.04

3.50 ± 1.51

0.542

4.50 ± 0.58

4.06 ± 0.91

5.00 ± 0.00

4.67 ± 0.58

0.274

Not able to finish meal

3.29 ± 1.54

4.09 ± 0.66

3.58 ± 1.05

3.00 ± 1.86

0.819

4.75 ± 0.50

3.58 ± 1.38

5.00 ± 0.00

4.67 ± 0.58

0.15

Loss of appetite

3.71 ± 0.97

2.38 ± 1.41

3.25 ± 1.04

2.83 ± 1.95

0.170

4.25 ± 0.96

3.17 ± 1.90

4.50 ± 0.71

5.00 ± 0.00

0.273

Bloating

3.43 ± 1.50

3.63 ± 1.19

3.75 ± 1.49

3.33 ± 1.72

0.882

3.25 ± 1.71

3.17 ± 1.47

5.00 ± 0.00

4.33 ± 0.58

0.196

Abdominal distension

2.89 ± 1.92

3.75 ± 0.46

3.38 ± 1.41

3.42 ± 1.78

0.873

2.25 ± 2.06

2.00 ± 1.60

5.00 ± 0.00

2.67 ± 0.58

0.153

Upper abdominal pain

3.14 ± 1.66

2.75 ± 2.25

3.00 ± 1.85

2.50 ± 1.93

0.848

3.00 ± 1.41

1.83 ± 1.64

4.00 ± 1.41

3.67 ± 0.58

0.130

Upper abd. discomfort

3.39 ± 1.47

2.00 ± 2.00

3.25 ± 1.16

3.17 ± 1.64

0.338

2.75 ± 1.26

2.00 ± 1.41

5.00 ± 0.00

4.00 ± 1.00

0.031*

Lower abdominal pain

2.43 ± 1.70

1.25 ± 1.67

2.56 ± 1.12

2.00 ± 1.65

0.239

3.25 ± 1.71

1.33 ± 1.44

3.50 ± 2.12

2.33 ± 0.58

0.128

Lower abd. discomfort

2.64 ± 1.78

1.63 ± 1.85

3.13 ± 0.35

1.83 ± 1.64

0.166

3.25 ± 1.71

1.92 ± 1.93

3.50 ± 2.12

2.67 ± 0.58

0.435

Heartburn during the day

2.21 ± 1.63

2.50 ± 1.41

1.63 ± 1.60

1.33 ± 1.87

0.299

2.75 ± 2.06

1.08 ± 1.56

1.00 ± 0.00

4.00 ± 1.00

0.080

Recumbent heartburn

2.29 ± 1.73

2.25 ± 1.83

1.63 ± 1.60

1.25 ± 1.91

0.366

3.00 ± 2.16

1.58 ± 1.78

0.50 ± 0.71

4.00 ± 1.00

0.140

Daytime chest discomfort

2.50 ± 1.61

1.63 ± 1.41

1.88 ± 1.36

1.42 ± 1.78

0.313

1.25 ± 1.26

1.00 ± 1.13

1.50 ± 0.71

3.33 ± 0.58

0.076

Recumbent chest discomfort

2.43 ± 1.79

1.25 ± 1.39

1.88 ± 1.13

1.25 ± 1.91

0.194

3.00 ± 2.16

1.00 ± 1.35

1.50 ± 0.71

3.00 ± 1.00

0.169

Daytime reflux

2.07 ± 1.94

2.63 ± 1.41

1.38 ± 1.06

1.75 ± 1.91

0.488

2.75 ± 1.89

1.58 ± 1.73

0.50 ± 0.71

3.00 ± 2.65

0.490

Nighttime reflux

1.86 ± 1.70

2.88 ± 1.64

1.50 ± 1.41

1.25 ± 1.66

0.179

3.25 ± 2.22

2.08 ± 2.07

0.50 ± 0.71

2.67 ± 2.08

0.487

Bitter taste

2.43 ± 1.74

2.13 ± 1.36

1.75 ± 1.67

1.83 ± 1.70

0.730

2.50 ± 1.73

1.33 ± 1.50

0.50 ± 0.71

2.67 ± 2.08

0.253

GCSI Total Score

3.44 ± 0.92

3.48 ± 0.59

3.27 ± 0.94

2.92 ± 1.15

0.550

3.37 ± 0.91

2.91 ± 0.89

4.07 ± 0.06

3.97 ± 0.38

0.068

PAGI-SYM Total Score

3.06 ± 0.91

2.74 ± 0.88

2.91 ± 0.89

2.49 ± 1.00

0.366

3.11 ± 1.20

2.27 ± 0.80

3.51 ± 0.53

3.58 ± 0.24

0.028*