Endoscopic features of oxyntic gland adenoma and gastric adenocarcinoma of the fundic gland type differ between patients with and without Helicobacter pylori infection: a retrospective observational study

Table 2 Comparison of the Hp and uninfected groups

	Hp group		Uninfected group		p value
	n	%	n	%	p value
Sex					0.550
Male	59	66.3	37	71.2
Female	30	33.7	15	28.8
Mean age ± SD, years	68.1 ± 8.1		63.4 ± 8.7		0.002
No. of lesions					0.091*
1	80	89.9	51	98.1
2	8	9.0	0	0.0
4	1	1.1	1	1.9
Mean size ± SD, mm	6.4 ± 4.5		6.6 ± 4.1		0.728
Depth of invasion					0.541^†
T1a (oxyntic gland adenoma)	56	56.0	27	49.1
T1b (GA-FG)	42	42.0	25	45.5
Not available	2	2.0	3	5.5
Location					0.001^‡
Fornix	26	26.0	28	50.9
Cardia	12	12.0	9	16.4
Body	62	62.0	17	30.9
Upper third of the body	30		10
Middle third of the body	26		4
Lower third of the body	6		3
Angle	0	0.0	1	1.8
Antrum	0	0.0	0	0.0
Pylorus	0	0.0	0	0.0
Morphology					0.003^§
0–I	1	1.0	1	1.8
0–IIa	53	53.0	41	74.5
0–IIb	34	34.0	10	18.2
0–IIc	10	10.0	1	1.8
0–IIa + IIc	2	2.0	2	3.6
0–III	0	0.0	0	0.0
Macroscopic appearance					< 0.001
SEL-like	42	42.0	43	78.2
Non SEL-like	58	58.0	12	21.8
Color					0.017^‖
Similar to the color of the peripheral mucosa	25	25.0	24	43.6
Reddish	11	11.0	9	16.4
Whitish	30	30.0	10	18.2
Yellowish–white	29	29.0	9	16.4
Yellowish	5	5.0	3	5.5
Vascular dilatation on the surface					0.250
Present	66	66.0	34	61.8
Absent	34	34.0	21	38.2
Black pigmentation on the surface					0.822
Present	15	15.0	9	16.4
Absent	85	85.0	46	83.6

The Hp group comprised patients with current Helicobacter pylori infection (active gastritis) and those with past infection (inactive gastritis). The uninfected group comprised H. pylori-uninfected patients
SD standard deviation, GA-FG gastric adenocarcinoma of the fundic gland type, SEL subepithelial lesion
*Solitary versus multiple lesions
^†T1a versus T1b
^‡Fornix and cardia versus others
^§Elevated (0–I, 0–IIa, or 0–IIa + IIc) versus depressed (other)
^‖Similar to the color of the peripheral mucosa versus other

ISSN: 1471-230X