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Table 2 Univariate and multivariate analyses to identify factors predicting severe PHLF

From: Comparative study of indocyanine green (ICG)-R15 and Albumin-Indocyanine Green Evaluation (ALICE) grading system in the prediction of posthepatectomy liver failure and postoperative mortality in patients with hepatic alveolar echinococcosis

 

Univariate analysis

Multivariate analysis

Characteristics

Odds ratio (95% CI)

P value

Odds ratio (95% CI)

P value

Serum albumin, g/L

0.809 (0.722–0.907)

 < 0.0001

1.280 (0.945–1.733)

0.111

Total bilirubin, μmol/L

1.075 (1.030–1.122)

0.001

1.050 (0.986–1.117)

0.130

INR

6.386 (0.698–58.393)

0.101

  

Child–Pugh score

2.607 (1.634–4.159)

 < 0.0001

0.985 (0.346–2.801)

0.977

ICG-R15, %

32.381 (8.454–124.026)

 < 0.0001

1.095 (0.952–1.259)

0.206

Lesion size, cm

1.218 (1.103–1.346)

 < 0.0001

0.969 (0.823–1.140)

0.704

operation time, hour

1.532 (1.278–1.837)

 < 0.0001

1.331 (1.028–1.724)

0.030

Multiple lesions

4.288 (1.582–11.623)

0.004

2.032 (0.367–11.247)

0.417

Major resection

8.696 (1.922–39.335)

0.005

2.548 (0.275–23.582)

0.410

Blood loss ≥ 500 mL

8.162 (2.604–25.583)

 < 0.0001

1.875 (0.362–9.706)

0.453

ALICE grade

13.936 (4.985–38.957)

 < 0.0001

15.975 (2.054–124.234)

0.008

  1. INR international normalized ratio; ICG indocyanine green; ICG‐R15 ICG retention test at 15 min