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Table 2 Univariate and multivariate analyses to identify factors predicting severe PHLF

From: Comparative study of indocyanine green (ICG)-R15 and Albumin-Indocyanine Green Evaluation (ALICE) grading system in the prediction of posthepatectomy liver failure and postoperative mortality in patients with hepatic alveolar echinococcosis

  Univariate analysis Multivariate analysis
Characteristics Odds ratio (95% CI) P value Odds ratio (95% CI) P value
Serum albumin, g/L 0.809 (0.722–0.907)  < 0.0001 1.280 (0.945–1.733) 0.111
Total bilirubin, μmol/L 1.075 (1.030–1.122) 0.001 1.050 (0.986–1.117) 0.130
INR 6.386 (0.698–58.393) 0.101   
Child–Pugh score 2.607 (1.634–4.159)  < 0.0001 0.985 (0.346–2.801) 0.977
ICG-R15, % 32.381 (8.454–124.026)  < 0.0001 1.095 (0.952–1.259) 0.206
Lesion size, cm 1.218 (1.103–1.346)  < 0.0001 0.969 (0.823–1.140) 0.704
operation time, hour 1.532 (1.278–1.837)  < 0.0001 1.331 (1.028–1.724) 0.030
Multiple lesions 4.288 (1.582–11.623) 0.004 2.032 (0.367–11.247) 0.417
Major resection 8.696 (1.922–39.335) 0.005 2.548 (0.275–23.582) 0.410
Blood loss ≥ 500 mL 8.162 (2.604–25.583)  < 0.0001 1.875 (0.362–9.706) 0.453
ALICE grade 13.936 (4.985–38.957)  < 0.0001 15.975 (2.054–124.234) 0.008
  1. INR international normalized ratio; ICG indocyanine green; ICG‐R15 ICG retention test at 15 min