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Table 5 Univariable and multivariable analysis of factors associated with survival in patients with HCC underwent TACE using Cox regression

From: Validation and prognostic value of EZ-ALBI score in patients with intermediate-stage hepatocellular carcinoma treated with trans-arterial chemoembolization

Univariate analysis Multivariate analysis
Factors HR 95%CI p-value Factors HR 95%CI p-value
Age 0.99 0.97–1.007 0.26     
Sex (male) 1.24 0.99–1.56 0.07     
MELD score 1.07 0.98–1.16 0.14     
Within up-to-seven criteria 0.92 0.68–1.26 0.62     
CTP B 1.17 0.69–1.99 0.57     
AFP > 20 ng/mL 1.82 1.16–2.85 0.009* AFP > 20 ng/mL 1.77 1.10–2.84 0.018*
Baseline EZ-ALBI
Grade 1
Grade 2
Grade 3
 
1.36–3.52
1.14–6.40

0.001*
0.023*
Baseline EZALBI
Grade 1
Grade 2
Grade 3
  -
1.24–3.88
1.24–8.57
-
0.007*
0.016*
1 (ref)
2.19
2.71
1 (ref)
2.20
3.26
Worsening EZ-ALBI grade 0.94 0.60–1.46 0.77     
  1. AFP Alpha fetoprotein, CI Confident interval, CTP Child-Turcotte-Pugh, EZ-ALBI Easy albumin-bilirubin, HR Hazard ratio, MELD Model for end-stage liver disease, ng/mL Nanogram per milliliter
  2. *Significant p-value is ≤ 0.05