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Table 5 Univariate and multivariate analysis of the elderly MPM patients

From: Clinical-pathological characteristics and prognostic factors for malignant peritoneal mesothelioma in the elderly

Variable Univariate analysis Multivariate analysis
Log-rank χ2 test P-value HR (95% CI) P value
Insurance status 26.663  < 0.001   
Insured    Reference  
Uninsured    5.187 (1.628–16.524) 0.005
Unknown    1.326 (1.100–1.600) 0.003
Histology 58.350  < 0.001   
Epithelioid    Reference  
Biphasic    2.279 (1.339–3.877) 0.002
Sarcomatoid    3.913 (2.347–6.523)  < 0.001
Unknown    2.301 (1.400–3.782) 0.012
Grade 39.596  < 0.001   
Well differentiated    Reference  
Moderately differentiated    1.978 (0.811–4.824) 0.134
Poorly differentiated    3.900 (2.194–6.933)  < 0.001
Undifferentiated    2.430 (1.038–5.689) 0.041
Unknown    2.301 (1.400–3.782) 0.001
Stage 23.936  < 0.001   
Localized    Reference  
Regional    1.244 (0.855–1.811) 0.254
Distant    1.735 (1.255–2.401) 0.001
Unknown    1.165 (0.792–1.713) 0.438
Surgery 43.605  < 0.001   
Cancer-directed surgery    Reference  
No cancer-directed surgery    1.733 (1.433–2.095)  < 0.001
Unknown    0.857 (0.435–1.689) 0.656
Chemotherapy 18.157  < 0.001   
Yes    Reference  
No or unknown    1.532 (1.282–1.831)  < 0.001
  1. Significant P values shown in bold
  2. MPM, malignant peritoneal mesothelioma; HR, hazard ratio; CI, confidential interval