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Table 1 Clinical characteristics of patients who received one-shot CDDP via HAI plus RT

From: Efficacy and safety of chemoradiation therapy using one-shot cisplatin via hepatic arterial infusion for advanced hepatocellular carcinoma with major macrovascular invasion: a single-arm retrospective cohort study

Characteristics

Median (range) or number of patients

Age (years)

69.5 (40–85)

Gender (male/female)

28/4

ECOG-Performance Status (0/1)

25/7

Etiology (HBV/HCV/HBV + HCV/other)

9/10/1/12

Total bilirubin (mg/dL)

0.9 (0.4–1.5)

Albumin (g/dL)

3.5 (2.6–4.6)

Prothrombin consumption test (%)

86.0 (6.2–111)

Child–Pugh score (5/6/7)

9/10/13

ALBI score

 − 2.17 (− 3.24– − 1.28)

mALBI grade (1/2a/2b/3)

5/7/19/1

Size of liver tumor (mm)

103.2 (36–185)

Number of intrahepatic tumors (< 4/ ≥ 4)

18/14

Relative tumor volume in the liver (< 50%/ ≥ 50%)

19/13

Vp (3/4)

13/15

Vv (0/1/2/3)

27/1/1/3

Extrahepatic spread (without/with)

22/10

HCC stage (III/IVa/IVb)a

4/6/22

BCLC stage (A/B/C)

0/0/32

Alpha-fetoprotein (ng/mL)

713.2 (1.3–3,686,000)

Des-γ-carboxy prothrombin (mAU/mL)

10,039 (36–327,600)

Additional systemic therapy (with/without)

23/9

  1. The clinical characteristics of the HCC patients with MVI who received one-shot CDDP chemotherapy via HAI plus RT. HCC hepatocellular carcinoma; MVI macrovascular invasion; HAI hepatic arterial infusion; CDDP cisplatin; HAI hepatic arterial infusion; RT radiation therapy; ECOG-Performance Status Eastern Cooperative Oncology Group Performance Status; HBV hepatitis B virus; HCC hepatocellular carcinoma; HCV hepatitis C virus; ALBI score = log10([total-bilirubin(mg/dL)]*17.1*0.66 − [albumin(g/dL)]*10*0.085; mALBI grade 1: 2a: 2b: 3 = ALBI score ≤  − 2.6: >  − 2.6 to <  − 2.27: ≥  − 2.27 to ≤  − 1.39: >  − 1.39; Vp portal vein invasion; Vv venous invasion; BCLC stage Barcelona Clinic liver cancer stage
  2. aAccording to the Liver Cancer Study Group of Japan