Skip to main content

Table 1 Demographic and disease characteristics in patients with ulcerative colitis (UC) with fatigue and none fatigue

From: Prevalence and factors associated with fatigue in patients with ulcerative colitis in China: a cross-sectional study

Variables Total (n = 220) Fatigue (n = 136) None fatigue(n = 84) P value
Gender, n (%)
Male 131 (59.5) 80 (58.8) 51 (60.7) 0.781
Female 89 (40.5) 56 (41.2) 33 (39.3)  
Age, year, median (IQR) 45 (33–56) 44 (32–56) 48 (35–57) 0.177
Education, n (%)
Master degree or above 9 (4.1) 5(3.7) 4(4.8) 0.861
Undergraduate 62 (28.2) 37 (27.2) 25 (29.8)  
Junior college 39 (17.7) 23 (16.9) 16 (19.0)  
Senior high school or below 110 (50.0) 71 (52.2) 39 (46.4)  
Employment status, n (%)
Full time or part time 151 (68.6) 91 (66.9) 60 (71.4) 0.134
No work 15 (6.8) 13 (9.6) 2 (2.4)  
Retired 37 (16.8) 20 (14.7) 17 (20.2)  
Other 17 (7.7) 12 (8.8) 5 (6.0)  
Only child, n (%)
Yes 70 (31.8) 47(34.6) 23(27.4) 0.267
No 150 (68.2) 89(65.4) 61 (72.6)  
Disease duration, year, median (IQR) 3.9 (1.3–7.9) 4.0 (1.4–8.0) 3.8 (1.1–6.7) 0.649
Montreal classification, n (%)
E1 39 (17.7) 16 (11.8) 23 (27.4)  < 0.001
E2 66 (30.0) 33 (24.3) 33 (39.3)  
E3 115 (52.3) 87 (64.0) 28 (33.3)  
Disease activity, n (%)
Remission 50 (22.7) 20 (14.7) 30 (35.7)  < 0.001
Mild 88 (40.0) 47 (34.6) 41 (48.8)  
Moderate 59 (26.8) 47 (34.6) 12 (14.3)  
Severe 23 (10.5) 22 (16.2) 1 (1.19)  
EIM, n (%)
Yes 65 (29.5) 38 (27.9) 27 (32.1) 0.507
No 155 (70.5) 98 (72.1) 57 (67.9)  
Complications, n (%)
Yes 12 (5.5) 5 (3.68) 7 (8.3) 0.241
No 208 (94.5) 131 (96.3) 77 (91.7)  
Medication have been used, n (%)
5-ASA 216 (98.2) 133 (97.8) 83 (98.8) 0.686
Immunosuppressants 10 (4.5) 6 (4.4) 4 (4.8)  
Corticosteroids 57 (25.9) 40 (29.4) 17 (20.2)  
Biologic treatment 8 (3.6) 5 (3.7) 3 (3.6)  
IBD related surgery, n (%)
Yes 10 (4.5) 8 (5.9) 2 (2.4) 0.226
No 210 (95.5) 128 (94.1) 82 (97.6)  
Anemia
Yes 49 (22.3) 38 (77.6) 11 (22.5) 0.01
No 171(77.7) 98 (57.3) 73 (42.7)  
Smoking status, n (%)
Yes 42(19.1) 26 (19.1) 16 (19.0) 0.99
No 178(80.9) 110 (80.9) 68 (81.0)  
Drinking status, n (%)
Yes 185 (80.1) 21 (15.4) 14 (16.7) 0.809
No 35 (15.9) 115 (84.6) 70 (83.3)  
BMI, n (%)
Thinnish 34 (15.5) 24 (17.6) 10 (11.9) 0.32
Normal 136 (61.8) 79 (58.1) 57 (67.9)  
Overweight or Obesity 50 (22.7) 33 (24.3) 17 (20.2)  
FSS, median (IQR) 4.4 (3.3–5.9) 5.4 (4.6–6.3) 2.7 (2.0–3.3)  < 0.001
MFI, median (IQR) 61 (48–73) 68.5 (60–78) 48 (37.3–58)  < 0.001
HAS, median (IQR) 5 (3–8) 7 (4–10) 4 (2–6)  < 0.001
HDS, median (IQR) 6 (3–9) 7 (4–10) 5 (2.25–7)  < 0.001
PSQI, median (IQR) 6 (4–9) 7 (5–10) 5 (3–8) 0.001
MUST, median (IQR) 1 (0–2) 1 (0–2) 0 (0–1) 0.001
  1. IQR indicates interquartile range, E1, Proctitis; E2, Left side colitis; E3, Extensive colitis; EIM extra-intestinal manifestations; 5-ASA 5-aminosalisylic acid, IBD inflammatory bowel disease, BMI body mass index, HAS hospital anxiety scale, HDS hospital depression scale, PSQI pittsburgh sleep quality index, MUST malnutrition universal screening tool