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Table 2 Univariate COX analysis for the potential predictors of ICU death in liver cirrhosis patients

From: Establishment of MELD-lactate clearance scoring system in predicting death risk of critically ill cirrhotic patients

Variables

β

SE

χ2

P

HR

95% CI

Lower

Upper

Age

0.007

0.005

1.668

0.196

1.007

0.997

1.017

Gender (Male)

 − 0.133

0.131

1.021

0.312

0.876

0.677

1.133

Insurance

       

Medicare

    

Ref

  

Others

0.062

0.159

0.151

0.697

1.064

0.779

1.453

Private

0.045

0.147

0.093

0.761

1.046

0.784

1.394

ICU type

       

MICU

    

Ref

  

CCU/CSRU

 − 0.219

0.202

1.175

0.278

0.803

0.540

1.194

SICU/TSICU

 − 0.368

0.147

6.215

0.013

0.692

0.519

0.924

Marital status

       

Married

    

Ref

  

Single

0.087

0.141

0.383

0.536

1.091

0.827

1.440

Widowed

0.049

0.284

0.030

0.863

1.050

0.602

1.831

Divorced/separated

0.061

0.200

0.092

0.761

1.063

0.717

1.574

Race

       

White

    

Ref

  

Black

0.236

0.206

1.319

0.251

1.267

0.846

1.896

Asian

0.759

0.343

4.890

0.027

2.136

1.090

4.187

Hispanic

 − 0.443

0.361

1.506

0.220

0.642

0.316

1.303

Others

 − 0.286

0.310

0.851

0.356

0.751

0.409

1.380

ACLF (Yes)

0.704

0.171

17.032

 < 0.001

2.021

1.447

2.823

Pathogenesis

       

Alcoholic

    

Ref

  

No alcoholic

0.233

0.389

0.360

0.549

1.263

0.589

2.705

Biliary

0.127

0.129

0.979

0.322

1.136

0.883

1.462

Hepatic encephalopathy (Yes)

 − 0.135

0.144

0.880

0.348

0.874

0.659

1.159

Ascites (Yes)

 − 0.026

0.135

0.036

0.849

0.975

0.748

1.270

Hepatocerebral syndrome (Yes)

0.159

0.155

1.050

0.306

1.172

0.865

1.587

RRT (Yes)

0.389

0.183

4.541

0.033

1.476

1.032

2.111

Vasopressors (Yes)

1.175

0.133

77.955

 < 0.001

3.239

2.495

4.205

Ventilation (Yes)

 − 0.128

0.127

1.012

0.314

0.880

0.685

1.129

Transplantation (Yes)

 − 2.511

0.710

12.494

 < 0.001

0.081

0.020

0.327

Temperature

 − 0.216

0.076

8.147

0.004

0.806

0.695

0.935

Heart rate

0.003

0.003

1.061

0.303

1.003

0.997

1.009

SBP

 − 0.008

0.003

5.315

0.021

0.992

0.986

0.999

DBP

 < 0.001

0.000

5.498

0.019

1.000

1.000

1.001

MAP

 − 0.008

0.004

4.727

0.030

0.992

0.985

0.999

SPO2/FiO2

 − 0.002

0.001

4.847

0.028

0.998

0.996

1.000

PaO2/FiO2

 − 0.002

0.000

19.165

 < 0.001

0.998

0.997

0.999

Bilirubin

0.027

0.006

23.490

 < 0.001

1.028

1.016

1.039

Creatinine

0.124

0.031

15.708

 < 0.001

1.132

1.065

1.203

INR

0.156

0.028

30.121

 < 0.001

1.169

1.105

1.235

PT

0.028

0.005

29.509

 < 0.001

1.028

1.018

1.039

Albumin

 − 0.362

0.094

14.827

 < 0.001

0.696

0.579

0.837

Glucose

 < 0.001

0.001

0.253

0.615

1.001

0.998

1.003

PH

 − 2.608

0.526

24.571

 < 0.001

0.074

0.026

0.207

Sodium

 − 0.043

0.009

22.916

 < 0.001

0.958

0.941

0.975

Potassium

0.173

0.062

7.936

0.005

1.189

1.054

1.342

Hemoglobin

 − 0.018

0.027

0.469

0.493

0.982

0.931

1.035

WBC

0.022

0.008

7.180

0.007

1.023

1.006

1.040

Chloride

 − 0.032

0.008

15.679

 < 0.001

0.969

0.954

0.984

PLT

 − 0.001

0.001

2.599

0.107

0.999

0.997

1.000

Lactate last

0.263

0.015

328.456

 < 0.001

1.301

1.265

1.339

Lactate first

0.117

0.018

43.252

 < 0.001

1.124

1.086

1.164

ΔLA

 − 0.350

0.038

85.886

 < 0.001

0.704

0.654

0.759

  1. ICU, intensive care unit; MICU, medical intensive care unit; CCU, coronary care unit; CSRU, cardiac surgery care unit; ICU, surgical intensive care unit; TSICU, traumatic surgical intensive care unit; ACLF, acute chronic liver failure; RRT, renal replacement therapy; SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure; PaO2, arterial oxygen partial pressure; FiO2, fraction of inspired oxygen; SPO2, pulse oxygen saturation; INR, international normalized ratio; PT, prothrombin time; PLT, platelet count; WBC, white blood cell count; ΔLA, lactate clearance;
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BMC Gastroenterology

ISSN: 1471-230X

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