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Table 4 Receiver operating characteristic curve analyses showing the utility of combined markers for differentiating between HCC and ICC

From: Utility of mean platelet volume in differentiating intrahepatic cholangiocarcinoma from hepatocellular carcinoma

Model

Sensitivity

Specificity

PPV

NPV

AUC

Development set

MPV

0.802

0.541

0.707

0.664

0.698 (0.646–0.746)

Combination

0.854

0.820

0.871

0.797

0.907 (0.870–0.935)

Validation set

MPV

0.863

0.523

0.889

0.463

0.757 (0.683–0.822)

Combination

0.860

0.882

0.939

0.750

0.931 (0.880–0.965)

  1. PPV, positive predictive value; NPV, negative predictive value; AUC, area under curve; Combination, five variables (sex, HBsAg, MPV, AFP, and CA19-9) were included in the model