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Table 4 Receiver operating characteristic curve analyses showing the utility of combined markers for differentiating between HCC and ICC

From: Utility of mean platelet volume in differentiating intrahepatic cholangiocarcinoma from hepatocellular carcinoma

Model Sensitivity Specificity PPV NPV AUC
Development set
MPV 0.802 0.541 0.707 0.664 0.698 (0.646–0.746)
Combination 0.854 0.820 0.871 0.797 0.907 (0.870–0.935)
Validation set
MPV 0.863 0.523 0.889 0.463 0.757 (0.683–0.822)
Combination 0.860 0.882 0.939 0.750 0.931 (0.880–0.965)
  1. PPV, positive predictive value; NPV, negative predictive value; AUC, area under curve; Combination, five variables (sex, HBsAg, MPV, AFP, and CA19-9) were included in the model