Fig. 2

A Infant “1”. Left: Esophagus on first endoscopic encounter with visible partial suture dehiscence. Middle: Day 28 of endoscopic vacuum therapy (EVT). The suture had torn open completely shortly after EVT initiation. Right: Day 39 of EVT. Complete defect closure achieved. Scar tissue visible. B Infant “2”. Left: Esophagus on first endoscopic encounter. Dehiscence of the esophageal anastomosis, involving two thirds of the circumference. Middle: Day 20 of EVT. Fibrin and necrotic tissue (grayish) and remainders of surgical sutures (purple) can be seen. Granulation tissue nodules (reddish and sanguineous) are considered as proof of EVT effectiveness. Right: 14 days after discharge from EVT. The leakage has completely healed but a stenosis has developed. C Infant “3”. Left: Perforation site a few hours after the percutaneous endoscopic gastrostomy (PEG) procedure. Middle: Day 4 of EVT. EVT has left a regular pattern of aspiration nubs. Right: 14 days after discharge from EVT. The defect is completely healed. Scar tissue can be seen. D Infant “4”. Left: Perforation site a few hours after PEG procedure. Middle: Day 4 of EVT with visibility of granulation tissue and aspiration nubs. Right: Day 11 of EVT with complete defect closure