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Table 1 Clinical characteristics of patients with pneumatosis intestinalis

From: Multicenter epidemiological survey of pneumatosis intestinalis in Japan

Characteristics n (%)
No. patients 167  
Men/women 87/80  
Median age of onset (years) 65 (range 9–91)  
Exposure to organic solvents 2 (1)
Comobidities and/or past medical history 141 (84)
 Gastroduodenal diseases 45 (27)
  Inflammatory bowel disease 16 (10)
   Ulcerative colitis 13 (8)
   Crohn's disease 2 (1)
   Behcet's disease 1 (1)
  Carcinoma 13 (8)
   Esophegeal carcinoma 1 (1)
   Gastric carcinoma 3 (2)
   Colorectal carcinoma 9 (5)
  Colorectal polyp 6 (4)
  Bowel obstruction 3 (2)
  Others 5 (3)
 Diabetes mellitus 31 (19)
 Chronic lung disease 28 (17)
 Autoimmune disease 30 (18)
 Hypertension 13 (8)
 Heart disease 11 (7)
 Hepatobiliarypancreatic disease 10 (6)
 Kideny disease 4 (2)
 Others 41 (25)
Medications used 137 (82)
 Corticosteroid 45 (27)
 Antidiabetics 29 (17)
  α-glucosidase inhibitors 23 (14)
  Others 14 (8)
 Gastric acid secretion inhibitors 20 (12)
  Proton pump inhibitors 15 (9)
  Histamine-2 receptor antagonists 6 (4)
 Antihypertensives 19 (11)
  Calcium antagonist 10 (6)
  β-blocker 8 (5)
  Angiotensin II receptor blocker 9 (5)
  Angiotensin converting enzyme inhibitor 1 (1)
  α-blocker 1 (1)
 Immunosuppressants 16 (10)
 5-aminosalicylates or salicylazosulfapyridine 15 (9)
 Statins/ezetimib/fibrates 14 (8)
 Antithrombotics 12 (7)
  Anticoagulants 4 (2)
  Antiplatelets 9 (5)
 Laxatives* 10 (6)
 Anti-cancer agents 9 (5)
 Herbal medicine 7 (4)
 Allopurinol/benzbromaron 3 (2)
 Others 44 (26)
  1. *Magnesium oxide (n = 7), sennoside (n = 4), and sodium picosulfate (n = 4)