Table 2 Evaluation of Mayo score, clinical response, clinical remission, endoscopic activity, and biochemical tests throughout treatment with anti-TNF therapy

Partial Mayo score

5.75 ± 2.33

3.36 ± 2.37*

2.46 ± 2.26*

1.89 ± 2.25*

Mayo endoscopic subscore

2.53 ± 0.61

–

1.43 ± 0.97*

1.08 ± 1.10*

Full Mayo score

8.37 ± 2.48

–

3.9 ± 2.76*

2.88 ± 2.86*

Clinical disease activity

Remission

8 (2.14)

90 (25.57)

115 (38.85)

162 (55.67)

Mild

46 (12.30)

145 (41.19)

97 (32.77)

79 (27.15)

Moderate

244 (65.24)

97 (27.56)

80 (27.03)

43 (14.78)

Severe

76 (20.32)

20 (5.68)

4 (1.35)

7 (2.41)

Clinical response

–

215 (61.25)

244 (83.85)

244 (87.46)

Clinical remission

54 (14.44)

235 (66.78) *

212 (71.62)

241 (82.82)

Mayo endoscopic subscore

0 - remission

3 (0.80)

–

47 (20.98)

120 (41.24)

1 - mild

15 (4.00)

–

65 (29.02)

72 (24.74)

2 - moderate

136 (36.27)

–

81 (36.16)

55 (18.90)

3- severe

221 (58.93)

–

31 (13.84)

44 (15.12)

Hematocrit (%)

35.78 ± 5.76

36.77 ± 5.02*

37.98 ± 4.99*

38.59 ± 4.67*

Hemoglobin (g/dl)

11.72 ± 2.08

12.14 ± 1.87*

12.56 ± 1.82*

12.75 ± 1.66*

Albumin (g/dl)

3.59 ± 0.62

3.78 ± 0.50*

3.85 ± 0.47*

3.99 ± 0.48*

C-reactive protein (mg/dl)

20.22 ± 35.26

9.42 ± 20.9*

7.09 ± 17.12*

5.54 ± 14.29*

Calprotectin (μg/g)

1360.14 ± 1853.06

583.66 ± 843.26*

374.47 ± 521.87*

327.05 ± 589.45*