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Table 1 Clinicopathological characteristics

From: Oncologic outcome of colon cancer with perforation and obstruction

  Perforation (n = 32) Obstruction (n = 22) P-value
Age, y 67.6 ± 15.2 64.1 ± 15.9 0.486
Sex    0.501
 Male 23 (72%) 15 (68%)  
 Female 9 (28%) 7 (32%)  
Follow-up, months 26.2 ± 21.6 26.6 ± 19.8 0.892
Location    0.895
 Rt sided colon 10 (28%) 6 (25%)  
 Lt-sided colon 22 (61%) 16 (67%)  
Stage    0.221
 II 13 (41%) 4(18%)  
 III 12 (37%) 11 (50%)  
 IV 7 (22%) 7 (32%)  
T stage    0.569
 3 15 (47%) 14 (64%)  
 4a 13 (41%) 6 (27%)  
 4b 4 (12%) 2 (9%)  
N stage    0.236
 0 14 (44%) 5 (23%)  
 1 10 (31%) 11 (50%)  
 2 8 (25%) 6 (27%)  
M stage    0.420
 0 25 (78%) 15 (68%)  
 1a 4 (12%) 5 (23%)  
 1b 1 (3%) 0 (0%)  
 1c 2 (6%) 2 (9%)  
Retrieved lymph nodes 24 ± 10 24 ± 9 0.560
OP name    0.107
 Rt.hemicolectomy 9 (36%) 6 (40%)  
 Ant.resection 3 (12%) 1 (7%)  
 Low. Ant. Resection 0 (0% 1 (7%)  
 Lt. hemicolectomy 1 (4%) 3( 20%)  
 Total colectomy 1 (4%) 2 (13%)  
 Hartmann's operation 11 (44%) 2 (13%)  
Complication    0.025*
 No 18 (56%) 18 (82%)  
 Wound complication 7 (22%) 0 (0%)  
 Pneumonia 1 (3%) 2 (9%)  
 Others 6 (19%) 2 (9%)  
Tumor size, cm 5.5 ± 2.2 5.2 ± 1.6 0.506
Histologic grade    0.019*
 Well, moderate 22 (69%) 21 (95%)  
 Poor, mucinous, others 10 (31%) 1 (5%)  
LVI, positive 18 (56%) 13 (59%) 0.593
PNI, positive 11 (34%) 10 (45%) 0.746
MLH1, positive 30 (94%) 17 (77%) 0.071
MSH2, positive 31 (97%) 17 (77%) 0.036*
KRAS mutant 12 (37%) 11 (50%) 0.222
ICU stay (Days) 4.9 ± 9 0.9 ± 1.1 0.018*
Adjuvant chemotherapy    0.286
 No 14 (44%) 5 (23%)  
 Yes 16 (50%) 16 (73%)  
 Unknown 2 (6%) 1 (4%)  
Tumor recurrence rate, % (except stage IV) 9/25 (36%) 1/15 (7%) 0.040*
Recurred tumor treatment    0.423
 No 1 0  
 Chemotherapy 5 0  
 Operation 2 1  
 Radiation 1 0  
Recurrence sites, % (except stage IV)    0.092
 Local 2/25 (8%) 0 (0%)  
 Systemic 7/25 (28%) 1 (7%)  
 No 16 (64%) 14 (93%)  
  1. Data are presented as n (%) or medians ± standard deviations
  2. LVI = lymphovascular invasion, PNI = perineural invasion, ICU = intensive care unit