Skip to main content

Table 1 Baseline case characteristics

From: Anticoagulant drugs with or without proton pump inhibitor and colorectal cancer risk: a population-based, case–control study

Variables

Total

(N = 52,405)

CRC

(N = 10,481)

Non-CRCa

(N = 41,924)

p Value

Gender, n

   

1.0000

 Male

30,760(58.70)

6152(58.70)

24,608(58.70)

 

 Female

21,645(41.30)

4329(41.30)

17,316(41.30)

 

Age, mean (± SD), yr

65.18 ± 12.62

65.18 ± 12.62

65.18 ± 12.62

 

Age group (n, %)

   

0.9997

  < 51

5990 (11.43)

1196 (11.41)

4794 (11.86)

 

 51–80

39,585 (75.54)

7922 (75.58)

31,663 (75.52)

 

  > 81

6830 (13.03)

1363 (13.01)

5467 (13.04)

 

BMI, mean (± SD), kg/m2

24.57 ± 3.88

24.34 ± 3.98

24.62 ± 3.86

 

BMI class (n, %)

   

 < 0.0001

  < 24

24,187(46.15)

5113(48.78)

19,074(45.50)

 

 25–30

23,639(45.11)

4479(42.73)

19,160(45.70)

 

  > 30

4579(8.74)

889(8.48)

3690(8.80)

 

Smoking (n, %)

   

0.4562

 Past smoker

262(0.50)

215(0.51)

47(0.45)

 

 Current smoker

65(0.12)

55(0.13)

10(0.10)

 

 Nonsmoker

52,078(99.38)

41,654(99.36)

10,424(99.46)

 

Alcohol (n, %)

   

0.1143

 Alcoholism

570(1.09)

441(1.05)

129(1.23)

 

 Non-alcoholism

51,835(98.91)

41,483(98.95)

10,352(98.77)

 

Comorbidities (n, %)

    

 Hypertension

13,985(26.69)

3356(32.02)

10,629(25.35)

 < 0.0001

 Diabetes Mellitus

8022(15.31)

1989(18.98)

6033(14.39)

 < 0.0001

 Cardiovascular disease

2106(4.02)

455(4.34)

1651(3.94)

0.0602

 Stroke

1786(3.41)

396(3.78)

1390(3.32)

0.0195

 Inflammatory bowel disease

61(0.12)

22(0.21)

39(0.09)

0.0017

 GI bleeding

2905(5.54)

1405(13.41)

1500(3.58)

 < 0.0001

  1. a Model was adjusted only for matching variables (age, gender, and year of index date), two groups classified present at 1:4 ratio