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Table 4 Combination of mSEPT9 and FIT in diagnosis of CRC

From: Methylated Septin9 has moderate diagnostic value in colorectal cancer detection in Chinese population: a multicenter study

 

mSEPT9+ AND FIT+

mSEPT9+ OR FIT+

Sensitivity

0.98 (0.94, 1.00)

0.69 (0.61, 0.77)

Specificity

0.69 (0.61, 0.75)

0.96 (0.91, 0.98)

PPV

0.72 (0.65, 0.78)

0.93 (0.86, 0.97)

NPV

0.98 (0.93, 1.00)

0.79 (0.73, 0.84)

Accuracy

0.82 (0.77, 0.86)

0.84 (0.79, 0.88)

AUC

0.83(0.79–0.87)

0.82 (0.78, 0.86)

  1. PPV Positive predictive value, NPV negative predictive value, AUC area under the curve
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BMC Gastroenterology

ISSN: 1471-230X

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