Table 3 Cox Proportional Multivariate Analysis for Baseline Characteristics of Patients with or without Severe Hepatotoxicity
Characteristics of the study population | Level | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
OR (95% CI) | P | OR (95% CI) | P | ||
Age group (Years) | < 30 | 1 | 0.02 | 1 | |
30–40 | 0.15 (0.03–0.65) | 0.16 (0.04–0.72) | 0.03 | ||
> 40 | 0.40 (0.11–1.47) | 0.32 (0.08–1.24) | 0.1 | ||
Gender | Male | 1 | 0.04 | 1 | |
Female | 0.26 (0.895.28) | 1.78 (0.58–5.49) | 0.32 | ||
Body Mass Index | Normal | 1 | 0.02 | 1 | |
Low | 0.38 (0.04–3.35) | 0.33 (0.11-0.99) | 0.04 | ||
Overweight | 0.30 (0.11-0.78) | 0.35 (0.21–4.59) | 0.11 | ||
Monthly income | < 50,000 | 1 | 0.01 | 1 | |
> 50,000 | 0.18 (0.04–0.86) | 0.14 (0.030.79) | 0.02 | ||
Alcohol intake | No | 1 | 0.07 | 1 | |
Yes | 0.40 (0.11-0.47) | 0.42 (0.09–1.64) | 0.1 | ||
Cigarette or tobacco intake | No | 1 | 0.09 | 1 | |
Yes | 2.26 (0.885.80) | 1.68 (0.51–5.60) | 0.39 | ||
CD4 Count values | < 200 | 1 | 0.06 | 1 | |
> 200 | 0.42 (0.16–1.08) | 0.65 (0.34–2.37) | 0.16 | ||
Name of ARV regimen | TDF + 3TC + EFV | 1 | 0.01 | 1 | |
AZT + 3TC + EFV | 0.25 (0.05–1.18) | 0.18 (0.03–0.99) | 0.22 | ||
AZT + 3TC + NVP | 2.86 (0.90–9.04) | 2.44 (0.58–10.26) | 0.03 | ||