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Table 4 Comparison of simple model and primary model

From: Combination of serological biomarkers and clinical features to predict mucosal healing in Crohn’s disease: a multicenter cohort study

Diagnostic Index

Simple model

(%, 95% CI)

Primary model

(%, 95% CI)

p Value

C-index

0.830

(0.79–0.87)

0.875

(0.84–0.91)

0.004*

Sensitivity

62.61%

(53.10–71.45%)

70.43%

(61.21- 78.58%)

0.467

Specificity

80.69%

(75.02–85.55%)

87.12%

(82.13- 91.14%)

0.448

PPV

61.54%

(54.29–68.31%)

72.97%

(65.45–79.37%)

0.292

NPV

81.39%

(77.39–84.81%)

85.65%

(81.76- 88.83%)

0.614

Accuracy

74.71%

(69.80–79.20%)

81.61%

(77.13–85.54%)

0.303

  1. *Statistically significant with a p-value less than 0.05
  2. Simple Model: model constructed from PLR, CAR and ESR; Primary Model: model constructed from PLR, CAR, ESR, HBI and IFX treatment; PPV, positive predictive value; NPV, negative predictive value; Bold indicates P < 0.05
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BMC Gastroenterology

ISSN: 1471-230X

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