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Table 2 AST, ALT, and AST/ALT ratio distribution among Hiroshima residents who had abdominal ultrasonography during check-up

From: Distribution of FIB-4 index in the general population: analysis of 75,666 residents who underwent health checkups

  N AST (IU/L) ALT (IU/L) AST/ALT (AAR)
  Mean ± SD Median Min–max AST ≥ 30 IU/L (%) Mean ± SD Median Min–max ALT ≥ 30 IU/L (%) Mean ± SD Median Min–max ALT/ALT > 1.0 (%)
Total population who received ultrasonography 5999 23.4 ± 12.0 21 8–363 15.4% 26.2 ± 20.6 20 2–503 26.5% 1.06 ± 0.39 1.0 0.26–7 47.8%
Non-drinkers without fatty liver 3781 20.9 ± 9.8* 19 8–363 7.6%# 20.6 ± 14.6* 18 2–503 13.4%# 1.15 ± 0.39* 1.1 0.26–7 60.0%#
Non-drinkers with fatty liver (NAFLD) 1399 28.0 ± 13.6* 25 11–167 30.8%# 40.7 ± 26.2* 33 7–291 59.4%# 0.78 ± 0.26* 0.73 0.34–2.47 14.8%#
p value   < 0.0001*     < 0.0001#  < 0.0001*     < 0.0001#  < 0.0001*     < 0.0001#
  1. AST alanine aminotransferase, ALT asparate aminotransferase, AAR AST/ALT ratio, SD standard deviation, NAFLD non-alcoholic fatty liver disease;
  2. *p value of the Wilcoxon test comparing the AST and ALT levels and AST/ALT ratios in non-drinkers without fatty liver and non-drinkers with fatty liver (NAFLD)
  3. #p value of the Chi-square test comparing the percentage of AST ≥ 30 IU/L, ALT ≥ 30 IU/L, and ALT/ALT > 1.0 in non-drinkers without fatty liver and non-drinkers with fatty liver (NAFLD)