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Table 2 AST, ALT, and AST/ALT ratio distribution among Hiroshima residents who had abdominal ultrasonography during check-up

From: Distribution of FIB-4 index in the general population: analysis of 75,666 residents who underwent health checkups

 

N

AST (IU/L)

ALT (IU/L)

AST/ALT (AAR)

 

Mean ± SD

Median

Min–max

AST ≥ 30 IU/L (%)

Mean ± SD

Median

Min–max

ALT ≥ 30 IU/L (%)

Mean ± SD

Median

Min–max

ALT/ALT > 1.0 (%)

Total population who received ultrasonography

5999

23.4 ± 12.0

21

8–363

15.4%

26.2 ± 20.6

20

2–503

26.5%

1.06 ± 0.39

1.0

0.26–7

47.8%

Non-drinkers without fatty liver

3781

20.9 ± 9.8*

19

8–363

7.6%#

20.6 ± 14.6*

18

2–503

13.4%#

1.15 ± 0.39*

1.1

0.26–7

60.0%#

Non-drinkers with fatty liver (NAFLD)

1399

28.0 ± 13.6*

25

11–167

30.8%#

40.7 ± 26.2*

33

7–291

59.4%#

0.78 ± 0.26*

0.73

0.34–2.47

14.8%#

p value

 

< 0.0001*

  

 < 0.0001#

 < 0.0001*

  

 < 0.0001#

 < 0.0001*

  

 < 0.0001#

  1. AST alanine aminotransferase, ALT asparate aminotransferase, AAR AST/ALT ratio, SD standard deviation, NAFLD non-alcoholic fatty liver disease;
  2. *p value of the Wilcoxon test comparing the AST and ALT levels and AST/ALT ratios in non-drinkers without fatty liver and non-drinkers with fatty liver (NAFLD)
  3. #p value of the Chi-square test comparing the percentage of AST ≥ 30 IU/L, ALT ≥ 30 IU/L, and ALT/ALT > 1.0 in non-drinkers without fatty liver and non-drinkers with fatty liver (NAFLD)