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Table 1 Distribution of FIB-4 index in those who received abdominal ultrasonography at health checkups in Japan

From: Distribution of FIB-4 index in the general population: analysis of 75,666 residents who underwent health checkups

 

Age (years)

N

FIB-4 index

 

Mean ± SD

Median

Min–Max

FIB4-index < 1.30 (%)

FIB4-index ≥ 2.67 (%)

Cochran-Armitage test for the proportion of FIB-4 index ≥ 2.67 by age group

Total population who received ultrasonography (N = 75,666)

< 50

32,103

0.82 ± 0.31

0.62

0.18–12.07

93.3

0.2

p < 0.0001

50–59

20,868

1.23 ± 0.44

1.16

0.17–15.39

68.9

0.8

60–69

16,854

1.60 ± 0.66

1.50

0.34–32.48

31.0

3.8

 ≥ 70

5841

2.10 ± 0.75

1.97

0.23–15.40

7.8

16.4

Overall

75,666

1.20 ± 0.63

1.07

0.17–32.48

65.3

2.3

 

Non-drinkers without fatty liver (N = 47,222)

 < 50

20,133

0.82 ± 0.28

0.78

0.21–6.64

94.9

0.1

p < 0.0001

50–59

11,946

1.24 ± 0.40

1.18

0.22–5.97

62.3

0.7

60–69

10,649

1.61 ± 0.63

1.53

0.44–32.48

27.9

3.4

 ≥ 70

4494

2.13 ± 0.75

2.01

0.23–15.40

6.8

17.3

Overall

47,222

1.23 ± 0.63

1.10

0.21–32.48

63.2

2.3

 

Non-drinkers with fatty liver (NAFLD) (N = 17,968)

 < 50

6934

0.75 ± 0.31

0.71

0.18–12.07

96.4

0.1

p = 0.0008

50–59

5559

1.13 ± 0.38

1.06

0.33–4.34

73.7

0.5

60–69

4350

1.48 ± 0.66

1.38

0.34–26.70

41.9

2.7

 ≥ 70

1125

1.92 ± 0.66

1.82

0.58–7.02

11.9

10.3

Overall

17,968

1.12 ± 0.58

1.01

0.18–26.70

70.9

1.6

 
  1. SD standard deviation, NAFLD non-alcoholic fatty liver disease
  2. The proportion of FIB-4 index ≥ 2.67, high risk of liver fibrosis, were compared by age group by the Cochran-Armitage test