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Table 1 Distribution of FIB-4 index in those who received abdominal ultrasonography at health checkups in Japan

From: Distribution of FIB-4 index in the general population: analysis of 75,666 residents who underwent health checkups

  Age (years) N FIB-4 index  
Mean ± SD Median Min–Max FIB4-index < 1.30 (%) FIB4-index ≥ 2.67 (%) Cochran-Armitage test for the proportion of FIB-4 index ≥ 2.67 by age group
Total population who received ultrasonography (N = 75,666) < 50 32,103 0.82 ± 0.31 0.62 0.18–12.07 93.3 0.2 p < 0.0001
50–59 20,868 1.23 ± 0.44 1.16 0.17–15.39 68.9 0.8
60–69 16,854 1.60 ± 0.66 1.50 0.34–32.48 31.0 3.8
 ≥ 70 5841 2.10 ± 0.75 1.97 0.23–15.40 7.8 16.4
Overall 75,666 1.20 ± 0.63 1.07 0.17–32.48 65.3 2.3  
Non-drinkers without fatty liver (N = 47,222)  < 50 20,133 0.82 ± 0.28 0.78 0.21–6.64 94.9 0.1 p < 0.0001
50–59 11,946 1.24 ± 0.40 1.18 0.22–5.97 62.3 0.7
60–69 10,649 1.61 ± 0.63 1.53 0.44–32.48 27.9 3.4
 ≥ 70 4494 2.13 ± 0.75 2.01 0.23–15.40 6.8 17.3
Overall 47,222 1.23 ± 0.63 1.10 0.21–32.48 63.2 2.3  
Non-drinkers with fatty liver (NAFLD) (N = 17,968)  < 50 6934 0.75 ± 0.31 0.71 0.18–12.07 96.4 0.1 p = 0.0008
50–59 5559 1.13 ± 0.38 1.06 0.33–4.34 73.7 0.5
60–69 4350 1.48 ± 0.66 1.38 0.34–26.70 41.9 2.7
 ≥ 70 1125 1.92 ± 0.66 1.82 0.58–7.02 11.9 10.3
Overall 17,968 1.12 ± 0.58 1.01 0.18–26.70 70.9 1.6  
  1. SD standard deviation, NAFLD non-alcoholic fatty liver disease
  2. The proportion of FIB-4 index ≥ 2.67, high risk of liver fibrosis, were compared by age group by the Cochran-Armitage test