Table 2 Univariate and multivariate analyses for overall survival in stage I colorectal cancer
From: Survival after curative resection for stage I colorectal mucinous adenocarcinoma
| Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| Mean OS (95% CI) | p value | HR (95% CI) | p value | |
| Gender | ||||
| Male | 1 | 0.604 | ||
| Female | 0.861 (0.489–1.517) | |||
| Age | ||||
| ≤ 65 | 1 | 0.012* | 2.217 (1.207–3.751) | 0.009* |
| > 65 | 2.030 (1.157–3.563) | |||
| Preoperative CEA | ||||
| ≤ 5 | 1 | 0.250 | ||
| > 5 | 1.596 (0.715–3.566) | |||
| T classification | ||||
| T 1 | 1 | 0.165 | ||
| T 2 | 1.606 (0.818–3.152) | |||
| Lesion location | ||||
| Colon | 1 | 0.021* | 3.213 (1.355–7.618) | 0.008* |
| Rectal | 2.628 (1.118–6.180) | |||
| Size | ||||
| < 3 cm | 1 | 0.884 | ||
| ≥ 3 cm | 0.959 (0.544–1.689) | |||
| Mucinous histology | ||||
| MAC | 1 | 0.479 | ||
| Non-MAC | 1.444 (0.519–4.016) | |||
| LVI | ||||
| (−) | 1 | < 0.001* | 6.283 (2.749–14.357) | < 0.001* |
| (+) | 4.666 (2.080–10.465) | |||
| Less than 12 lymph nodes | ||||
| Yes | 1 | 0.935 | ||
| No | 1.031 (0.499–2.130) | |||
| dMMR | ||||
| Positive | 1 | 0.042* | 2.618 (1.025–6.685) | 0.044* |
| Negative | 0.395 (0.156–0.998) | |||