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Table 2 Univariate and multivariate analyses for overall survival in stage I colorectal cancer

From: Survival after curative resection for stage I colorectal mucinous adenocarcinoma

Variable Univariate analysis Multivariate analysis
  Mean OS (95% CI) p value HR (95% CI) p value
Gender     
 Male 1 0.604   
 Female 0.861 (0.489–1.517)    
Age     
 ≤ 65 1 0.012* 2.217 (1.207–3.751) 0.009*
 > 65 2.030 (1.157–3.563)    
Preoperative CEA     
 ≤ 5 1 0.250   
 > 5 1.596 (0.715–3.566)    
T classification     
 T 1 1 0.165   
 T 2 1.606 (0.818–3.152)    
Lesion location     
 Colon 1 0.021* 3.213 (1.355–7.618) 0.008*
 Rectal 2.628 (1.118–6.180)    
Size     
 < 3 cm 1 0.884   
 ≥ 3 cm 0.959 (0.544–1.689)    
Mucinous histology     
 MAC 1 0.479   
 Non-MAC 1.444 (0.519–4.016)    
LVI     
 (−) 1 < 0.001* 6.283 (2.749–14.357) < 0.001*
 (+) 4.666 (2.080–10.465)    
Less than 12 lymph nodes     
 Yes 1 0.935   
 No 1.031 (0.499–2.130)    
dMMR     
 Positive 1 0.042* 2.618 (1.025–6.685) 0.044*
 Negative 0.395 (0.156–0.998)    
  1. The bold and *  indicates p < 0.05
  2. MAC mucinous adenocarcinomas, CEA carcinoembryonic antigen, dMMR deficient mismatch repair