Ontology function/activity place | p value | Colon up | Intestine up | Stomach up | Ontology function/activity place | p value | Colon up | Intestine up | Stomach up |
---|---|---|---|---|---|---|---|---|---|
Cellular response to cytokine stimulus | 0.011 | 0.00% | 9.09% | 0.00% | Negative regulation of protein localization to nucleus | 0.032 | 0.85% | 9.09% | 0.00% |
Socs1 | Trim40 | Trim40 | |||||||
Cellular response to organic cyclic compound | 0.032 | 0.85% | 9.09% | 0.00% | Negative regulation of signal transduction | 0.02 | 0.85% | 13.64% | 2.56% |
Btrc | Socs1 | Socs5 |
Socs1 Socs3 |
Cish Socs5 | |||||
Cytokine-mediated signaling pathway | 0.02 | 0.85% | 13.64% | 2.56% | Negative regulation of tyrosine phosphorylation of STAT protein | 0.001 | 0.00% | 13.64% | 0.00% |
Socs5 |
Socs1 Socs3 Cish | Socs5 |
Socs1 Socs3 | ||||||
Cytoplasmic ribonucleoprotein granule | 0.011 | 0.00% | 9.09% | 0.00% | Positive regulation of I-kappaB kinase/NF-kappaB signaling | 0.042 | 1.69% | 13.64% | 2.56% |
Socs1 |
Mul1 Trim62 |
Mul1 Rnf31 Trim30 |
Trim13 Trim62 | ||||||
IkappaB kinase complex | 0.032 | 0.85% | 9.09% | 0.00% | Positive regulation of regulatory T cell differentiation | 0.011 | 0.00% | 9.09% | 0.00% |
Trim40 | Trim40 | Socs1 | |||||||
Insulin-like growth factor receptor binding | 0.011 | 0.00% | 9.09% | 0.00% | Protein kinase inhibitor activity | 0.02 | 0.85% | 13.64% | 2.56% |
Socs1 | Socs5 |
Socs1 Socs3 |
Socs5 Cish | ||||||
Intracellular signal transduction | 0.049 | 3.39% | 18.18% | 5.13% | Protein neddylation | 0.032 | 0.85% | 9.09% | 0.00% |
Socs5 Spsb4 Wsb1 |
Socs1 Socs3 Wsb1 |
Asb2 Cish Socs5 | Trim40 | Trim40 | |||||
JAK-STAT cascade | 0.042 | 1.69% | 13.64% | 2.56% | Regulation of activation of Janus kinase activity | 0.011 | 0.00% | 9.09% | 0.00% |
Pias1 Socs5 |
Socs1 Socs3 |
Pias1 Socs5 | Socs1 | ||||||
Negative regulation of insulin receptor signaling pathway | 0.002 | 0.00% | 13.64% | 1.28% | Regulation of cytokine secretion | 0.011 | 0.00% | 9.09% | 0.00% |
Socs1 Socs3 | Cish | Socs1 | |||||||
Negative regulation of JAK-STAT cascade | 0.02 | 0.85% | 13.64% | 2.56% | Regulation of interferon-gamma-mediated signaling pathway | 0.011 | 0.00% | 9.09% | 0.00% |
Socs5 |
Socs1 Socs3 |
Cish Socs5 | Socs1 | ||||||
Negative regulation of NF-kappaB transcription factor activity | 0.032 | 0.85% | 9.09% | 0.00% | Regulation of JAK-STAT cascade | 0.011 | 0.00% | 9.09% | 0.00% |
Trim40 | Trim40 | Socs1 | |||||||
Negative regulation of protein catabolic process | 0.032 | 0.85% | 9.09% | 0.00% | Regulation of protein phosphorylation | 0.001 | 0.00% | 13.64% | 0.00% |
Trim40 | Trim40 |
Socs1 Socs3 | |||||||
Negative regulation of protein kinase activity | 0.02 | 0.85% | 13.64% | 2.56% | Regulation of tyrosine phosphorylation of STAT protein | 0.011 | 0.00% | 9.09% | 0.00% |
Socs5 |
Socs1 Socs3 |
Socs5 Cish | Socs1 |