Table 1 Baseline characteristics of the study participants (N = 9837)
Characteristics | Quartiles of UHR | P value | ||||
|---|---|---|---|---|---|---|
Q1 (≤ 120.88) | Q2 (120.89–154.01) | Q3 (154.02–189.91) | Q4 (189.92–240.46) | Q5 (≥ 240.47) | ||
Gender Male/Female (n) | 902/1065 | 924/1045 | 957/1009 | 1086/882 | 1136/831 |  < 0.001 |
Age (years) Mean ± SD | 41.83 ± 12.27 | 41.99 ± 14.58 | 42.29 ± 14.66 | 43.16 ± 15.09 | 43 ± 14.87 | 0.011 |
NAFLD onset n (%) | 47 (2.4%) | 98 (5%) | 156 (7.9%) | 203 (10.3%) | 351 (17.8%) |  < 0.001 |
ALP (U/L) Median (Quartile) | 58.00 (49.00–69.00) | 62.00 (52.00–76.00) | 68.00 (56.00–82.00) | 71.00 (60.00–85.00) | 74.00 (62.00–87.00) |  < 0.001 |
ALT (U/L) Median (Quartile) | 13.00 (11.00–17.00) | 14.00 (11.00–19.00) | 15.00 (12.00–21.00) | 17.00 (12.00–22.00) | 18.00 (13.00–24.00) |  < 0.001 |
AST (U/L) Median (Quartile) | 19.00 (17.00–22.00) | 20.00 (17.00–23.00) | 21.00 (18.00–24.00) | 21.00 (18.00–25.00) | 22.00 (19.00–26.00) |  < 0.001 |
TP (g/L) Mean ± SD | 73.28 ± 4.07 | 73.58 ± 3.99 | 73.83 ± 4.04 | 74.04 ± 4.12 | 74.18 ± 4.22 |  < 0.001 |
ALB (g/L) Mean ± SD | 43.87 ± 2.72 | 44.09 ± 2.60 | 44.38 ± 2.83 | 44.61 ± 2.73 | 44.73 ± 2.80 |  < 0.001 |
GLB (g/L) Mean ± SD | 29.44 ± 3.69 | 29.57 ± 3.70 | 29.53 ± 3.93 | 29.47 ± 3.82 | 29.49 ± 4.18 |  < 0.001 |
TB (μmol/L) Median (Quartile) | 11.00 (8.00–14.00) | 11.00 (9.00–14.00) | 11.00 (9.00–14.00) | 12.00 (9.00–16.00) | 12.00 (10.00–16.00) |  < 0.001 |
BUN (mmol/L) Median (Quartile) | 4.20 (3.50–5.05) | 4.20 (3.50–5.10) | 4.30 (3.51–5.10) | 4.40 (3.60–5.26) | 4.40 (3.70–5.30) |  < 0.001 |
Cr (μmol/L) Median (Quartile) | 66.00 (59.00–72.00) | 68.00 (60.50–76.00) | 72.00 (62.00–86.00) | 83.00 (68.00–95.00) | 90.00 (79.00–101.00) |  < 0.001 |
UA (mmol/L) Mean ± SD | 176.34 ± 34.98 | 221.96 ± 35.03 | 254.95 ± 42.10 | 296.73 ± 46.36 | 369.55 ± 61.84 |  < 0.001 |
FPG (mmol/L) Mean ± SD | 4.97 ± 0.58 | 5.02 ± 0.70 | 5.08 ± 0.82 | 5.12 ± 0.73 | 5.17 ± 0.64 |  < 0.001 |
TC (mmol/L) Mean ± SD | 4.39 ± 0.51 | 4.35 ± 0.51 | 4.36 ± 0.54 | 4.33 ± 0.54 | 4.27 ± 0.54 |  < 0.001 |
TG (mmol/L) Mean ± SD | 0.81 ± 0.25 | 0.89 ± 0.28 | 0.96 ± 0.30 | 1.05 ± 0.31 | 1.13 ± 0.30 |  < 0.001 |
HDL-C (mmol/L) Median (Quartile) | 1.79 (1.62–1.99) | 1.60 (1.45–1.78) | 1.41 (1.31–1.65) | 1.37 (1.24–1.52) | 1.23 (1.13–1.36) |  < 0.001 |
LDL-C (mmol/L) Median (Quartile) | 1.99 (1.71–2.27) | 2.07 (1.81–2.35) | 2.17 (1.88–2.43) | 2.19 (1.90–2.46) | 2.25 (1.94–2.52) |  < 0.001 |
Height (m) Mean ± SD | 160.53 ± 5.49 | 161.56 ± 6.58 | 163.73 ± 7.44 | 166.66 ± 7.69 | 169.21 ± 7.26 |  < 0.001 |
Weight (kg) Mean ± SD | 52.04 ± 5.85 | 53.76 ± 6.81 | 56.36 ± 7.77 | 59.33 ± 7.93 | 63.01 ± 7.99 |  < 0.001 |
BMI (kg/m2) Median (Quartile) | 20.10 (18.87–21.52) | 20.53 (19.27–21.94) | 21.04 (19.56–22.46) | 21.41 (19.86–22.88) | 22.21 (20.66–23.59) |  < 0.001 |
SBP (mmHg) Median (Quartile) | 112.00 (103.00–120.00) | 113.00 (104.00–122.00) | 116.00 (106.00–127.00) | 119.00 (109.00–131.00) | 122.00 (113.00–134.00) |  < 0.001 |
DBP (mmHg) Median (Quartile) | 68.00 (62.00–74.00) | 68.00 (62.00–75.00) | 70.00 (64.00–78.00) | 72.00 (65.00–80.00) | 73.00 (67.00–85.25) |  < 0.001 |