Nuclear morphometry and chromatin texture changes in hepatocellular carcinoma samples may predict outcomes of liver transplanted patients

Table 3 Morphometric and chromatin texture characteristics

Characteristic	Tumor—mean (Standard deviation)	Adjacent—mean (Standard deviation)	p*
Nuclear shape descriptors
Area (µm²)	48.65 ± 14.90	53.51 ± 7.13	0.066
Perimeter (µm)	26.08 ± 4.06	24.07 ± 2.22	0.025
Circularity	0.833 ± 0.04	0.955 ± 0.01	< 0.001
Feret (µm)	85.33 ± 14.78	89.80 ± 5.69	0.094
ncMGV (µm)	22.64 ± 9.83	25.18 ± 6.33	0.206
Solidity	0.982 ± 0.009	0.995 ± 0.002	< 0.001
AR	1.28 ± 0.08	1.15 ± 0.06	< 0.001
Chromatin texture descriptor
Fractal dimension	1.16 ± 0.03	1.19 ± 0.02	0.001

*p, statistical significance; µm micrometer, ncMGV normalized corrected mean grey value, AR aspect ratio

ISSN: 1471-230X