Table 2 Predictive factors for cervical LN metastasis (144 cases)
Predictors | Univariate analysis | Multivariable analysis | ||
|---|---|---|---|---|
P | OR (95% CI) | P | OR (95% CI) | |
Gender | 1.00 |  | – |  |
 Male |  | Reference |  | – |
 Female |  | 1.00 (0.44–2.27) |  | – |
Age, years | 0.47 | 0.99 (0.94–1.05) | – | – |
Tumor location | 0.17 |  | – |  |
 Middle |  | Reference |  | – |
 Lower |  | 0.46 (0.16–1.30) |  | – |
Degree of differentiation | 0.82 |  | – |  |
 Well |  | Reference |  | – |
 Moderate |  | 1.29 (0.38–4.35) |  | – |
 Poorly |  | 0.98 (0.26–3.74) |  | – |
Maximum diameter of tumor |  < 0.01 | 1.43 (1.14–1.80) |  < 0.01 | 1.46 (1.11–1.92) |
Depth of tumor invasion | 0.06 |  | – |  |
 T1 |  | 0.37 (0.08–1.75) |  | – |
 T2 |  | Reference |  | – |
 T3 |  | 1.51 (0.50–4.61) |  | – |
 T4 |  | 2.29 (0.58–9.02) |  | – |
PLN status |  < 0.01 |  |  < 0.01 |  |
 Negative |  | Reference |  | Reference |
 Positive |  | 4.80 (2.01–11.43) |  | 3.94 (1.45–10.68) |
MLN status |  < 0.01 |  | – |  |
 Negative |  | Reference |  | – |
 Positive |  | 3.88 (1.51–9.98) |  | – |
RLN LN status |  < 0.01 |  |  < 0.01 |  |
 Negative |  | Reference |  | Reference |
 Positive |  | 5.05 (2.26–11.30) |  | 3.82 (1.56–9.34) |
ALN status | 0.84 |  | – |  |
 Negative |  | Reference |  | – |
 Positive |  | 1.14 (0.51–2.54) |  | – |
Blood vessel invasion | 0.12 |  | – |  |
 Negative |  | Reference |  | – |
 Positive |  | 2.66 (0.91–7.75) |  | – |
Nerve invasion | 0.29 |  | – |  |
 Negative |  | Reference |  | – |
 Positive |  | 1.77 (0.68–4.61) |  | – |
CT-reported cervical LN status |  < 0.01 |  |  < 0.01 |  |
 Negative |  | Reference |  | Reference |
 Positive |  | 3.41 (1.46–7.94) |  | 4.43 (1.60–12.27) |