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Fig. 2 | BMC Gastroenterology

Fig. 2

From: Steroid-mediated liver steatosis is CD1d-dependent, while steroid-induced liver necrosis, inflammation, and metabolic changes are CD1d-independent

Fig. 2Fig. 2

The therapeutic effect of GC on existing metabolic and liver damage was studied in four groups of C57BL/6 mice. Mice in group D received the vehicle alone; Group E received Dexamethasone; Group F received a combination of Dexamethasone with GC; mice in group G received Dexamethasone for six weeks followed by two weeks of Dexamethasone with GC. Mice were followed for fasting glucose levels (a); postprandial glucose levels as manifested by glucose tolerance test (b); serum insulin levels (c); serum triglyceride levels (d); AST and ALT liver enzymes (e); liver histology (H&E X10) (f); hepatic triglycerides content (g); and for serum levels of IL10 and IL17 (h) (**p < 0.01, *p < 0.05)

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