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Table 1 The Clinicopathological characteristics of patients with RES after ESD and univariate analysis of endoscopic treatment success

From: Long-term outcomes of refractory esophageal strictures after endoscopic submucosal dissection of superficial esophageal neoplasms

Category

 

N (%)/M (range)

Success no

P&

Sex

Female

27 (54)

14

0.203

 

Male

23 (46)

16

 

Age (years)

65.5 (45–77)

-

0.921

Smoking history

13 (26)

9

0.430

Drinking history

12 (24)

7

0.892

Depth of in infiltration

m1

20 (40)

16

0.200

 

m2

14 (28)

6

 
 

m3

12 (24)

6

 
 

sm1

2 (4)

1

 
 

sm2

2 (4)

1

 

Tumor location*

Cervical

31 (62)

18

0.721

 

Thoracic

19 (38)

12

 

Postoperative pathology

HGIN

20 (40)

12

0.322

 

SCC

30 (60)

18

 

Length of lesion (cm)

9 (2–19)

-

0.652

Circumferential ratio

1/2–1

18 (36)

13

0.122

 

1

32 (64)

17

 

Operating time (min)

102 (40–261)

0.318

En bloc Resection

50 (100)

30

-

Muscular injury

21 (42)

14

0.413

Clip

4 (8)

2

0.670

Coagulation

24 (48)

19

0.008

Dilation times

6 (3–33)

0.763

Length of strictures (cm)

4 (1–9)

0.643

Number of strictures

One

43 (86)

23

0.020

 

Two or more

7 (14)

7

 

R0 resection

34 (50)

20

0.558

Dysphagia-free period (days)

42 (7–863)

0.550

Pre-dilation period (days)

51 (9–276)

0.001

Therapy

Dilation + Oral Prednisone

27 (54)

10

 < 0.001

 

Dilation only

23 (46)

20

 
 

Bougie dilator

11 (22)

20

0.022

 

Balloon dilator only

39 (78)

10

 
 

Stents

7 (14)

5

0.506

Pre-dilation dysphagia score

4 (1–4)

0.098

Post-dilation dysphagia score

1 (0–4)

 < 0.001

  1. RES: Refractory esophageal strictures
  2. *The location of oral-lateral lesion
  3. &P indicates a significant relationship between characteristics of patients and endoscopic therapy successes in univariate analysis