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Table 7 Univariate and multivariate analyses for predicting ascites

From: Comparison of operative outcomes between monopolar and bipolar coagulation in hepatectomy: a propensity score-matched analysis in a single center

Variables

Ascites

Multivariate analysis

Yes (n = 26)

No (n = 120)

P value

OR

95% CI

P value

Age

70 (31–79, 13)

69 (33–87, 15)

0.276

   

Sex (male/female)

19/7

84/36

0.755

   

BMI

21.3 (18.3–26.9, 4.5)

22.9 (15.4–37.1, 4.5)

0.162

   

ASA (1 or 2/3)

20/6

104/16

0.214

   

Diagnosis (HCC/non-HCC)

22/4

65/55

0.007

3.442

0.751–15.768

0.111

Background liver condition (hepatitis/normal)

21/5

60/60

0.007

1.246

0.292–5.328

0.766

Type of resection (major hepatectomya/minor hepatectomyb)

19/7

90/30

0.838

   

Number of resected lesions

1 (1–3, 1)

1 (1–16, 0)

0.979

   

Size of the largest nodule on preoperative imagingc (cm)

2.3 (0.9–20.0, 2.7)

2.5 (0.5–12.0, 2.0)

0.582

   

Number of nodules on preoperative imagingc

1 (1–10, 2)

1 (1–10, 0)

0.204

   

Lymph node dissection (yes/no)

3/23

17/103

0.724

   

Biliary reconstruction (yes/no)

1/25

10/110

0.444

   

Neoadjuvant chemotherapy (yes/no or previous)

2/24

19/101

0.295

   

Total bilirubin (mg/dL) (≥ 1.1/ < 1.1)

8/18

25/95

0.276

   

Aspartate transaminase (IU/L) (≥ 31/ < 31)

16/10

58/62

0.225

   

Albumin (g/dL) (≥ 3.9/ < 3.9)

13/13

81/39

0.095

   

Prothrombin activity (%) (≥ 69/ < 69)

22/4

118/2

0.008

0.275

0.032–2.330

0.236

Activated partial thromboplastin time (%) (≥ 69/ < 69)

22/4

105/15

0.692

   

Hemoglobin (g/dL) (≥ 11.4/ < 11.4)

21/5

96/24

0.929

   

Platelet (× 104/μL) (≥ 15.3/ < 15.3)

8/18

80/40

0.010

0.359

0.123–1.050

0.061

Blood urea nitrogen (mg/dL) (≥ 20.0/ < 20.0)

5/21

16/104

0.440

   

Creatinine (mg/dL) (≥ 1.07/ < 1.07)

3/23

20/100

0.518

   

C-reactive proteind (mg/dL) (≥ 0.14/ < 0.14)

10/15

40/63

0.915

   

ICGR15e (%) (≥ 10/ < 10)

19/7

71/43

0.588

   

Child–Pugh score

5 (5–6, 1)

5 (5–8, 0)

0.006

0.509

0.191–1.354

0.176

Total operative time (min)

257 (123–673, 167)

253 (74–670, 115)

0.397

   

Transection timef (min)

96 (19–262, 77)

84 (15–298, 63)

0.682

   

Pringle maneuverg (min)

54 (18–158, 51)

58 (15–159, 31)

0.962

   

Blood loss (mL)

565 (35–8030, 997)

550 (0–5940, 629)

0.269

   

Red blood cell transfusion (mL)

0 (0–3360, 90)

0 (0–2850, 0)

0.218

   

Hemostatic device (monopolar/bipolar)

20/6

53/67

0.004

5.626

1.881–16.827

0.002

  1. Continuous data are presented as median (range, interquartile range), whereas categorical data are shown as number of patients. Significant P-values are in boldface
  2. BMI, body mass index; ASA, American Society of Anesthesiologists; HCC, hepatocellular carcinoma; ICGR15, indocyanine green retention rate at 15 min; OR, odds ratio; CI, confidence interval
  3. aMajor hepatectomy indicates more than one section hepatectomy excluding left lateral hepatectomy
  4. bMinor hepatectomy indicates partial and left lateral hepatectomy
  5. cData on the size of the largest nodule and number of nodules were partially lacking because biliary tract cancer and benign disease could not be accurately measured (with ascites, 24 cases; without ascites, 110 cases)
  6. dData on C-reactive protein were partially lacking (with ascites, 25 cases; without ascites, 103 cases)
  7. eData on ICGR15 were partially lacking (with ascites, 26 cases; without ascites, 114 cases)
  8. fData on total transection time were partially lacking (with ascites, 21 cases; without ascites, 105 cases)
  9. gData on total Pringle maneuver time were partially lacking (with ascites, 19 cases; without ascites, 80 cases)