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Table 4 Multivariate analysis of factors associated with CDI in Hospitalized IBD patients according to CDI defined by lab dataset or hospitalization admission and discharge database (DAD)

From: Effect of clinical versus administrative data definitions on the epidemiology of C. difficile among hospitalized individuals with IBD: a population-based cohort study

 

Lab dataset

DAD

Odds ratio (95% CI)

p-value

Odds Ratio (95% CI)

p-value

5-ASA

1.30 (0.81–2.10)

0.28

1.65 (1.02–2.65)

0.040

Corticosteroids

1.71 (1.05–2.79)

0.031

1.37 (0.82–2.28)

0.23

Any antibiotic

2.21 (1.37–3.56)

0.001

2.78 (1.70–4.54)

 < 0.001

Prior hospital admission

2.00 (1.18–3.39)

0.010

2.24 (1.32–3.79)

0.003

Charlson Comorbidity index Score

    

0

Reference

 

Reference

 

1

0.67 (0.34–1.34)

0.26

1.01 (0.52–1.95)

0.98

2

1.72 (0.82–3.58)

0.15

1.45 (0.67–3.14)

0.34

3 + 

0.83 (0.35–1.94)

0.66

0.91 (0.42–1.96)

0.80

Ambulatory care

    

Lowest quartile

Reference

 

Reference

 

2nd quartile

1.25 (0.55–2.84)

0.60

1.19 (0.50–2.83)

0.69

3rd quartile

2.29 (1.03–5.08)

0.042

2.14 (0.95–4.81)

0.067

Highest quartile

2.07 (0.85–5.04)

0.11

2.34 (0.96–5.72)

0.063

  1. aAmbulatory care frequency quartiles: Quartile 1 0–8, Quartile 2 9–16, Quartile 3 17–27, Quartile 4 28 + 
  2. *Bolded p-values are statistically significant