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Table 2 Median faecal calprotectin levels in colorectal neoplasia

From: The role of faecal calprotectin in diagnosis and staging of colorectal neoplasia: a systematic review and meta-analysis

Author Year n Median
Total Normal (%) Adenoma (%) AA (%) CRC (%) Normal Adenoma AA CRC
Roseth 1992 111 33 (29.7) 8 (7.2) 2025 μg/l 40000 μg/l
Roseth 1993 206 113 (54.8) 53 (27.7) 50 mg/l
Gilbert 1996 18 4 (22.2) 14 (77.8) 5 mg/l 33 mg/l
Kristinsson 1998 119 119 (100) 5.2 mg/l 50 mg/l
Kronborg 2000 814 488 (60.0) 203 (24.9) 23 (2.8) 6.6 mg/l 9.1 mg/l 17.6 mg/l
Ton 2000 238 59 (24.8) 149 (62.6) 26 μg/g 372 μg/g
Kristinsson 2001 237 114 (48.1) 73 (30.8) 17 (7.2) 5 (2.1) 11.5 mg/l 14 mg/l 18 mg/l
Tibble 2001 233 96 (41.2) 29 (12.4) 62 (26.6) 2.3 mg/l 12 mg/l 101 mg/l
Summerton 2002 134 28 (20.9) 6 (4.5) 8 (6.0) 4.5 mg/l 3.8 mg/l 53.5 mg/l
Tibble 2002 602 7 (1.2) 47 mg/l
Hoff 2004 2321 1518 (65.4) 592 (25.5) 195 (8.4) 16 (0.7) 21.5 μg/g 24 μg/g 66.1 μg/g
Chung-Faye 2007 148 7 (4.7) 15 μg/g 105 μg/g
Damms 2008 140 56 (40.0) 29 (20.7) 8 (5.7) 25.8 μg/g 66.3 μg/g 164 μg/g
Karl 2008 551 252 (45.7) 113 (20.5) 186 (33.8) 22.4 μg/g 27.2 μg/g 420.5 μg/g/ 350.3 μg/g
Kok 2012 382 112 (29.3) 53 (13.9) 16 (4.2) 19 (5.0) 46 μg/g 71 μg/g 89 μg/g 274 μg/g
Manz 2012 538 314 (58.4) 50 (9.3) 17 (3.2) 10 μg/g 101 μg/g 104 μg/g
Khoshbaten 2014 150 50 (33.3)    50 (33.3) 19.3 μg/g    19.3 μg/g
Lehman 2014 80 80 (100) 205 μg/g
Wang 2014 40 20 20 (100) 116 IU/ml 179.1 IU/ml
Turvill 2016 654 39 (6.0) 272 μg/g
Widlak 2016 430 42 (9.8) 24 (5.6) 145 μg/g
Cubiella 2016 1572 214 (13.6) 120 ng/ml
  1. CRC colorectal cancer, AA advanced adenoma