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Table 1 Studies reporting faecal calprotectin assays in the context of colorectal neoplasia

From: The role of faecal calprotectin in diagnosis and staging of colorectal neoplasia: a systematic review and meta-analysis

References Year Manufacturer Test Units Cut-off Standardised cut-off
Roseth [18] 1992   EIA μg/l   
Roseth [21] 1993   EIA mg/l 10 mg/l 50
Gilbert [22] 1996 Nycomed Pharma ELISA mg/l 10 mg/l 50
Kristinsson [23] 1998   EIA mg/l 10 mg/l 50
Kronborg [24] 2000 Nycomed Pharma ELISA, PhiCal mg/l 10 mg/l 50
Ton [11] 2000 Nycomed Pharma ELISA, PhiCal mg/l 10 mg/l 50
Kristinsson [16] 2001 Nycomed Pharma ELISA, PhiCal mg/l 10 mg/l 50
Tibble [25] 2001   ELISA mg/l 10 mg/l 50
Kristinsson [26] 2001 Nycomed Pharma ELISA, PhiCal mg/l 10 mg/l 50
Summerton [27] 2002 Nycomed ELISA, PhiCal mg/l 10 mg/l 50
Tibble [28] 2002   ELISA mg/l 10 mg/l 50
Costa [29] 2003 Eurospital ELISA, Calprest μg/g 50 μg/g 50
Limburg [30] 2003 Nycomed Pharma ELISA μg/g 50 μg/g 50
Hoff [31] 2004 Nycomed Pharma ELISA, PhiCal μg/g 50 μg/g 50
Chung-Faye [32] 2007   ELISA μg/g 25 μg/g 25
Damms[33] 2008 Bühlmann ELISA μg/g 50 μg/g 50
Karl [34] 2008 NovaTec ELISA μg/g   
Meucci [35] 2010 Eurospital ELISA, Calprest mg/dl 50 mg/dl  
Kalimutho [36] 2011 Eurospital ELISA, Calprest ng/ml 45.8 ng/ml  
Kok [37] 2012 Bühlmann ELISA, EK-CAL μg/g 50 μg/g 50
Manz [38] 2012 Bühlmann ELISA μg/g 50 μg/g 50
Parente [39] 2012 Bühlmann ELISA μg/g 50 μg/g 50
Pavlidis [40] 2013 Bühlmann ELISA, EK-CAL μg/g 50 μg/g 50
Khoshbaten [41] 2014 Bühlmann ELISA μg/g 75.8 μg/g 75.8
Lehmann [42] 2014 Viollier ELISA μg/g 50 μg/g 50
Wang [43] 2014 Labsystem ELISA IU/ml   
Borza [44] 2015 Sofar Farmaceutici Cal-Detect SOFAR (Semi-quantitative) mg/g 15 mg/g  
Mowat [45] 2015 Bühlmann ELISA, EK-CAL μg/g 50 μg/g 50
Cubiella [46] 2016 Bühlmann ELISA, fCAL ng/ml   
Rutka [47] 2016 Bühlmann Quantum Blue μg/g 128.5 μg/g 128.5
Turvill [48] 2016 Bühlmann ELISA, EK-CAL μg/g 50 μg/g 50
Widlak [49] 2016 Thermo Fisher Scientific ELISA, EliA μg/g 50 μg/g 50
Hogberg [50] 2017 Calpro AS ELISA, CALPRO μg/g 100 μg/g 100
Turvill [51] 2018 Bühlmann ELISA, EK-CAL μg/g 10 μg/g 10
Lue [52] 2020 Thermo Fisher Scientific ELISA, EliA μg/g 50 μg/g 50
  1. EIA enzyme immunoassay, ELISA enzyme-linked immunosorbent assay, mg/l milligrams/litre, mg/dl milligrams/ desilitre, μg/g microgram/gram, ng/ml nanogram/millilitre, IU/ml international unit/millilitre, Standardised Cut-off μg/g or mg/l multiplied by 5