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Fig. 4 | BMC Gastroenterology

Fig. 4

From: Corticosteroid suppresses urea-cycle-related gene expressions in ornithine transcarbamylase deficiency

Fig. 4

The gene expression levels related with catabolism and anabolism in WT and Otcspf−ash muscles administered DEX or NS. a Quantitative RT-PCR analysis of the anabolism-related genes. b Quantitative RT-PCR analysis of the catabolism-related genes. c Quantitative RT-PCR analysis of the autophagy-related genes. The gene expression levels normalized to those of WT-NS and were presented as mean ± SE. p < 0.05 and p < 0.01. PI3K, phosphatidylinositol-3 kinase; mTOR, mammalian target of rapamycin; 4E-BP1, Eukaryotic translation initiation factor 4E-binding protein 1; eIF4E, eukaryotic translation initiation factor 4E; Rps6kb1, Ribosomal Protein S6 Kinase B1; FOXO1, forkhead box protein O1; KLF15, Kruppel Like Factor 15; MuRF-1, Muscle RING-finger protein-1; ULK1, Unc-51 Like Autophagy Activating Kinase 1; ATG, Autophagy related. NS; normal saline, DEX; dexamethasone

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