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Table 1 Comparison of differences for the clinicopathological parameters in low or high Foxp3+ Tregs intratumor or TDLNs

From: Correlation and prognostic implications of intratumor and tumor draining lymph node Foxp3+ T regulatory cells in colorectal cancer

 

Intratumor

TDLNs

Low

High

P

Low

High

P

Age (years)

  

< 0.01

  

0.17

 < 60

36

31

 

41

26

 

 ≥ 60

64

19

 

60

23

 

Gender

  

1.00

  

0.47

 Female

37

19

 

40

16

 

 Male

63

31

 

61

33

 

Tumor location

  

0.41

  

0.15

 Right side

21

14

 

20

15

 

 Left side

79

36

 

81

34

 

Histological grade

  

< 0.01

  

0.65

 Well + moderate

77

48

 

83

42

 

 Poor

23

2

 

18

7

 

CEA status

  

0.16

  

0.59

 Normal

57

35

 

60

32

 

 Elevated

43

15

 

41

17

 

Invasive depth

  

< 0.01

  

0.03

 T1+2

14

21

 

18

17

 

 T3+4

86

29

 

83

32

 

Tumor diameter (cm)

  

0.22

  

0.48

 < 4

37

24

 

39

22

 

 ≥ 4

63

26

 

62

27

 

Node involvement(s)

  

0.73

  

< 0.01

 N0

56

30

 

50

36

 

 N1+2

44

20

 

51

13

 

Distant metastasis

  

1.00

  

0.27

 M0

94

47

 

93

48

 

 M1

6

3

 

8

1

 

TNM stages

  

0.49

  

0.02

 I + II

53

30

 

49

34

 

 III + IV

47

20

 

52

15

 

BMI (kg/m2)

23.48 ± 3.86

23.65 ± 3.69

0.78

23.53 ± 3.45

23.56 ± 4.47

0.96

Pre-operative measurements

      

 NLR

2.53 ± 2.80

2.32 ± 1.23

0.63

2.34 ± 1.27

2.71 ± 3.78

0.13

 LMR

3.89 ± 1.53

4.34 ± 1.79

0.11

3.95 ± 1.61

4.24 ± 1.67

0.30

 PNI

48.60 ± 6.12

48.33 ± 5.63

0.79

48.34 ± 6.07

48.87 ± 5.70

0.60

  1. Statistical differences were shown in bold