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Table 3 Univariate and multivariate analyses of the clinicopathological characteristics for PFS

From: Combined systemic immune-inflammatory index (SII) and prognostic nutritional index (PNI) predicts chemotherapy response and prognosis in locally advanced gastric cancer patients receiving neoadjuvant chemotherapy with PD-1 antibody sintilimab and XELOX: a prospective study

Independent factor

Univariate analysis

Multivariate analysis

Hazard ratio

95% CI

P value

Hazard ratio

95% CI

P value

Sex

0.532

   

 Female

1.000

Reference

    

 Male

1.176

0.625–1.621

    

Age (years)

0.243

   

 < 60

1.000

Reference

    

 ≥ 60

1.242

0.913–1.751

    

Tumor response

0.002

  

0.002

 Non-TRG3

1.000

Reference

 

1.000

Reference

 

 TRG3

6.379

3.231–9.127

 

4.429

2.742–7.421

 

SII-PNI score

0.001

  

0.003

 0

1.000

Reference

 

1.000

Reference

 

 1

1.889

1.346–3.692

 

1.967

0.875–2.928

 

 2

3.576

2.328–6.246

 

2.758

1.167–4.276

 

Tumor size (cm)

0.002

  

0.020

 < 5.0

1.000

Reference

 

1.000

Reference

 

 ≥ 5.0

2.512

1.351–4.392

 

2.059

1.431–4.821

 

Differentiation

0.001

  

0.009

 Poor

1.000

Reference

 

1.000

Reference

 

 Well

2.256

1.256–3.344

 

3.499

1.874–7.748

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