Independent factor | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
Hazard ratio | 95% CI | P value | Hazard ratio | 95% CI | P value | |
Sex | 0.532 | Â | Â | Â | ||
 Female | 1.000 | Reference |  |  |  |  |
 Male | 1.176 | 0.625–1.621 |  |  |  |  |
Age (years) | 0.243 | Â | Â | Â | ||
 < 60 | 1.000 | Reference |  |  |  |  |
 ≥ 60 | 1.242 | 0.913–1.751 |  |  |  |  |
Tumor response | 0.002 | Â | Â | 0.002 | ||
 Non-TRG3 | 1.000 | Reference |  | 1.000 | Reference |  |
 TRG3 | 6.379 | 3.231–9.127 |  | 4.429 | 2.742–7.421 |  |
SII-PNI score | 0.001 | Â | Â | 0.003 | ||
 0 | 1.000 | Reference |  | 1.000 | Reference |  |
 1 | 1.889 | 1.346–3.692 |  | 1.967 | 0.875–2.928 |  |
 2 | 3.576 | 2.328–6.246 |  | 2.758 | 1.167–4.276 |  |
Tumor size (cm) | 0.002 | Â | Â | 0.020 | ||
 < 5.0 | 1.000 | Reference |  | 1.000 | Reference |  |
 ≥ 5.0 | 2.512 | 1.351–4.392 |  | 2.059 | 1.431–4.821 |  |
Differentiation | 0.001 | Â | Â | 0.009 | ||
 Poor | 1.000 | Reference |  | 1.000 | Reference |  |
 Well | 2.256 | 1.256–3.344 |  | 3.499 | 1.874–7.748 |  |