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Table 6 Relation between antiviral treatment and the odds of HCC in HBV, ALD + HBV and ALD + HCV patients

From: Effect of alcohol on clinical complications of hepatitis virus-induced liver cirrhosis: a consecutive ten-year study

Variables

n (%)

OR

95% CI

P value

HBV

    

 No AVT

4246/9620 (44.1)

1

  

 AVT

168/863 (19.5)

0.31

0.26–0.36

<  0.001

HCV

    

 No AVT

71/251 (28.3)

1

  

 AVT

71/431 (16.5)

0.50

0.34–0.73

<  0.001

ALD + HBV

    

 No AVT + no abst

431/592 (72.8)

1

  

 No AVT + abst

71/275 (25.8)

0.13

0.10–0.18

<  0.001

 AVT + no abst

32/79 (40.5)

0.25

0.16–0.41

<  0.001

 AVT + abst

13/60 (21.7)

0.10

0.05–0.20

<  0.001

ALD + HCV

    

 No AVT + no abst

48/105 (45.7)

1

  

 No AVT + abst

8/28 (28.6)

0.47

0.19–1.17

0.107

 AVT + no abst

33/87 (37.9)

0.73

0.41–1.29

0.278

 AVT + abst

6/60 (10.0)

0.13

0.05–0.33

<  0.001

  1. HCC, Hepatocellular carcinoma; AVT, antiviral treatment; abst, alcohol abstinence; HBV, hepatitis B virus; HCV, hepatitis C virus; ALD, alcohol-induced liver disease; ALD + HCV, co-existing ALD and HCV. Only patients with information on AVT were included in this analysis