Table 2 Manometric findings of patients undergoing high resolution esophageal manometry with impedance testing, including all patients and patients stratified by presence or absence of pathologic reflux on HREMI (table excludes patients who did not undergo ambulatory pH reflux monitoring, did not have upper GI symptoms or did not complete questionnaire on GI symptoms)
From: Characterizing reflux on high resolution esophageal manometry with impedance
Manometric Findings | All patients (n = 229) | Patients with reflux on HREMI (n = 47) | Patients without reflux on HREMI (n = 182) | p value |
|---|---|---|---|---|
UES basal pressure (mmHg) (nl. 34–104 mmHg) | 75.4 ± 2.7 | 80.8 ± 7.6 | 74.0 ± 5.5 | 0.843 |
UES residual pressure (mmHg) (< 12 mmHg) | 3.0 ± 0.3 | 4.6 ± 0.7 | 2.6 ± 0.2 | 0.029 |
UES mean peak pressure (mmHg) (nl. < 19.5 mmHg) | 12.9 ± 0.6 | 13.0 ± 1.3 | 12.8 ± 1.0 | 0.601 |
DCI (nl. 450–8000 mmHg.s.cm) | 1632.2 ± 112.6 | 1396.0 ± 231.3 | 1677.7 ± 124.4 | 0.460 |
LES basal pressure (nl. 13–43 mmHg) | 26.5 ± 1.0 | 16.3 ± 1.9 | 29.2 ± 2.2 | < 0.001 |
IRP (nl. < 15 mmHg) | 10.1 ± 0.5 | 6.4 ± 1.1 | 11.0 ± 0.8 | 0.001 |
EGJ type II/III morphology | 111 (48.5%) | 36 (76.6%) | 75 (41.2%) | < 0.001 |
Bolus clearance (normal > 80%) | 60.7 ± 2.4% | 69.0 ± 4.4 | 58.5 ± 4.3 | 0.353 |
Chicago classification | ||||
EGJOO | 28 (12.2%) | 1 (2.1%) | 27 (20.5%) | 0.001 |
Major Disorders | 41 (17.9%) | 3 (6.4%) | 38 (19.5%) | |
Minor Disorders/no abnormalities | 160 (87.8%) | 43 (91.5%) | 117 (60%) | |