No | Age/sex | Clinical presentation | Upper gastrointestinal endoscopy | Endoscopic ultrasound | Size (cm) | metastasis | Pathology | Treatment | Follow-up outcome |
---|---|---|---|---|---|---|---|---|---|
1 | 65/male | Dysphagia, weight loss | Concentric narrowing of the oesophagus | – | 4–5 | None | Cancer cells originated from squamous epithelial cysts in the oesophageal wall | Chemoradiotherapy | 7 weeks Patient died |
2 | 58/male | Dysphagia |  | No unequivocal findings | 3 | Resection margin positive | Poorly differentiated squamous cell carcinoma, infiltrating all layers of the oesophageal wall | Surgery + radiochemotherapy | 13 months in fine general condition |
3 | 58/male | Dysphagia, weight loss | – | – | 7 × 5 × 5 | None | Squamous epithelial malignancy lacking glandular formation | Surgery | 6 months in fine general condition |
4 | 45/female | Dysphagia, weight loss | Smooth stricture with normal overlying mucosa | Heteroechoic mass lesion in submucosa | 3.3 × 2.5 | Bone | Squamous cell carcinoma beneath t normal epithelium | Palliative chemoradiotherapy | 2 months No change in the size of the tumour |
5 | 60/male | Dysphagia | Small mass in the oesophagus and a large submucosal mass in the gastric cardia | – | – | Gastric | Oesophageal squamous cell carcinoma with submucosal growth pattern | Surgery | 110 days Patient died |
6 | 63/male | Abdominal distension | Mucosal eminence with normal overlying mucosa | Heterogeneous and hypoechoic in muscularis mucosa or submucosa | 1.3 × 1.0 × 0.3 | Vertical margin positive | Under normal epithelium, atypical cells with an increased nuclear-to-cytoplasmic ratio could be seen | ESD + radiotherapy | 2 years No recurrence or metastasis |
7 | 65/male | Dysphagia | Hemispherical lesion with smooth mucosa | Hypoechoic and heterogeneous echotexture in the submucosa | 1.5 × 1.5 × 1.0 | None | Atypical squamous cell clusters could be seen under normal epithelium | ESD | 1 year No recurrence and metastasis |