Elevated average maximum intrabolus pressure on high-resolution manometry is associated with esophageal dysmotility and delayed esophageal emptying on timed barium esophagram

Table 1 Manometry and timed barium esophagram (TBE) in case-cohort and control-cohort

Manometry	Cases	Controls	p-value
Number of patients	114	41
Age (years); Mean ± SD	61.3 ± 13.0	55.1 ± 15.4	0.75
BMI; Mean ± SD	29.9 ± 5.5	28.5 ± 6.7	0.75
Sex, N (%)			0.01
Male	47 (41.2%)	8 (19.5%)
Female	67 (58.8%)	33 (80.5%)
Hernia, N (%)	34 (29.8%)	20 (48.8%)	0.003
Size (cm); Mean ± SD	2.9 ± 1.9	3.0 ± 1.4	0.89

TBE	Cases	Controls	p-value
Total, N	114	41
Normal	40	29	< 0.001
Abnormal^a	74	12
Tablet arrest, N (%)	41 (36.0%)	4 (9.8%)	< 0.001
Hiatal hernia, N (%)	5 (4.4%)	4 (9.8%)	< 0.001
Stricture, N (%)	3 (2.6%)	0 (0%)	–
TBE 1' N
Column > 0 mm, N (%)	54 (48.2%)	10 (24.4%)	0.003
Mean ± SD (mm)	53 (73.9%)	27 (59.4%)	0.43925
TBE 5' N
Column > 0 mm, N (%)	37 (32.7%)	2 (4.9%)	< 0.001
Mean ± SD (mm)	26.3 (49.3)	2.4 (13.1%)	0.44

^aPlease see Fig. 2 for further elaboration of the classification of abnormal subtypes

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