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Table 1 Clinical characteristics of the patients

From: Models to predict the short-term survival of acute-on-chronic liver failure patients following liver transplantation

Characteristics ALL(n = 132) Survival(n = 113) Death(n = 19) P value
Age, mean ± SD (years) 45.92 ± 11.07 45.50 ± 11.04 48.37 ± 11.26 0.30
Etiologies, n(%)     0.29
HBV 111(84.1%) 96(85.0%) 15(78.9%)  
Cholestasis 6(4.5%) 4(3.5%) 2(10.5%)  
Alcohol 7(5.3%) 7(6.2%) 0(0%)  
Other 8(6.1%) 2(1.8%) 6(31.6%)  
Male, n(%) 108(81.8%) 94(83.2%) 14(73.7%) 0.51
ACLF Score     
CLIF-ACLF grade, n(%)     0.22
Grade 1 5(3.8%) 5(4.4%) 0(0%)  
Grade 2 91(68.9%) 80(70.8%) 11(57.9%)  
Grade 3 36(27.3%) 28(24.8%) 8(42.1%)  
TBILI, mean ± SD (μmol/L) 401.64 ± 198.29 404.00 ± 201.33 387.61 ± 183.55 0.74
Cr, mean ± SD (μmol/L) 84.71 ± 51.07 78.23 ± 37.09 123.26 ± 92.67 0.05
INR, mean ± SD 2.53 ± 1.22 2.44 ± 1.13 3.07 ± 1.58 0.11
HE, n(%) 29(22.0%) 23(20.4%) 6(31.6%) 0.27
PT, mean ± SD (s) 28.98 ± 13.95 28.28 ± 13.28 33.19 ± 17.24 0.25
Urea, mean ± SD (mmol/L) 7.83 ± 11.60 7.04 ± 11.20 12.54 ± 13.11 0.06
Alb, mean ± SD (g/L) 34.56 ± 5.68 34.43 ± 5.76 35.34 ± 5.30 0.52
DBiL, mean ± SD (μmol/L) 239.56 ± 131.65 244.93 ± 133.54 207.62 ± 117.93 0.26
Hb, mean ± SD (g/L) 105.07 ± 23.52 105.44 ± 23.19 102.90 ± 25.98 0.67
Plt, mean ± SD (10^3cells/μL) 92.53 ± 78.81 93.78 ± 82.80 85.05 ± 49.73 0.66
WBC, mean ± SD (10^3cells/μL) 8.06 ± 4.42 7.80 ± 4.19 9.59 ± 5.49 0.10
LYM, mean ± SD (10^3cells/μL) 1.09 ± 0.77 1.12 ± 0.78 0.92 ± 0.70 0.31
NEUT, mean ± SD (10^3cells/μL) 6.21 ± 3.80 5.95 ± 3.71 7.78 ± 4.05 0.05
Intensive Care Unit, n (%) 25(18.9%) 18(15.9%) 7(36.8%) 0.031
Renal replacement therapy, n (%) 7(5.3%) 3(2.7%) 4(21.1%) 0.001
Multidrug resistant organism infection, n (%) 3(2.3%) 2(1.8%) 1(5.3%) 0.344
Donor age, years 39.78 ± 13.25 40.50 ± 12.90 35.42 ± 14.82 0.51
Cause of death     0.09
Trauma 68(51.5%) 60(53.1%) 8(42.1%)  
Cerebrovascular accident (CVA) 49(37.1%) 43(38.1%) 6(31.6%)  
Other 15(11.4%) 10(8.8%) 5(26.3%)  
Donor risk index 1.40 ± 0.27 1.40 ± 0.23 1.38 ± 0.22 0.37
Steatosis     0.38
 < 5% 38(28.8%) 30(26.5%) 8(42.1%)  
5% ~ 15% 70(53.0%) 62(54.9%) 8(42.1%)  
15% ~ 30% 24(18.2%) 21(18.6%) 3(15.8%)  
Cold ischemia time 7.52 ± 2.01 7.45 ± 1.97 7.89 ± 2.28 0.64
  1. Tested by Student’s t-test or Pearson’s chi-squared (χ2) test; SD Standard Deviation; HBV Hepatitis B Virus; TBiL total bilirubin; Cr creatinine; INR International Normalized Ratio; HE hepatic encephalopathy; PT prothrombin time; Alb albumin; DBiL Direct Bilirubin; Hb hemoglobin; Plt platelet; WBC White Blood Cells; LYM lymphocyte count; NEUT neutrophil count