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Table 1 Clinical characteristics of the patients

From: Models to predict the short-term survival of acute-on-chronic liver failure patients following liver transplantation

Characteristics

ALL(n = 132)

Survival(n = 113)

Death(n = 19)

P value

Age, mean ± SD (years)

45.92 ± 11.07

45.50 ± 11.04

48.37 ± 11.26

0.30

Etiologies, n(%)

   

0.29

HBV

111(84.1%)

96(85.0%)

15(78.9%)

 

Cholestasis

6(4.5%)

4(3.5%)

2(10.5%)

 

Alcohol

7(5.3%)

7(6.2%)

0(0%)

 

Other

8(6.1%)

2(1.8%)

6(31.6%)

 

Male, n(%)

108(81.8%)

94(83.2%)

14(73.7%)

0.51

ACLF Score

    

CLIF-ACLF grade, n(%)

   

0.22

Grade 1

5(3.8%)

5(4.4%)

0(0%)

 

Grade 2

91(68.9%)

80(70.8%)

11(57.9%)

 

Grade 3

36(27.3%)

28(24.8%)

8(42.1%)

 

TBILI, mean ± SD (μmol/L)

401.64 ± 198.29

404.00 ± 201.33

387.61 ± 183.55

0.74

Cr, mean ± SD (μmol/L)

84.71 ± 51.07

78.23 ± 37.09

123.26 ± 92.67

0.05

INR, mean ± SD

2.53 ± 1.22

2.44 ± 1.13

3.07 ± 1.58

0.11

HE, n(%)

29(22.0%)

23(20.4%)

6(31.6%)

0.27

PT, mean ± SD (s)

28.98 ± 13.95

28.28 ± 13.28

33.19 ± 17.24

0.25

Urea, mean ± SD (mmol/L)

7.83 ± 11.60

7.04 ± 11.20

12.54 ± 13.11

0.06

Alb, mean ± SD (g/L)

34.56 ± 5.68

34.43 ± 5.76

35.34 ± 5.30

0.52

DBiL, mean ± SD (μmol/L)

239.56 ± 131.65

244.93 ± 133.54

207.62 ± 117.93

0.26

Hb, mean ± SD (g/L)

105.07 ± 23.52

105.44 ± 23.19

102.90 ± 25.98

0.67

Plt, mean ± SD (10^3cells/μL)

92.53 ± 78.81

93.78 ± 82.80

85.05 ± 49.73

0.66

WBC, mean ± SD (10^3cells/μL)

8.06 ± 4.42

7.80 ± 4.19

9.59 ± 5.49

0.10

LYM, mean ± SD (10^3cells/μL)

1.09 ± 0.77

1.12 ± 0.78

0.92 ± 0.70

0.31

NEUT, mean ± SD (10^3cells/μL)

6.21 ± 3.80

5.95 ± 3.71

7.78 ± 4.05

0.05

Intensive Care Unit, n (%)

25(18.9%)

18(15.9%)

7(36.8%)

0.031

Renal replacement therapy, n (%)

7(5.3%)

3(2.7%)

4(21.1%)

0.001

Multidrug resistant organism infection, n (%)

3(2.3%)

2(1.8%)

1(5.3%)

0.344

Donor age, years

39.78 ± 13.25

40.50 ± 12.90

35.42 ± 14.82

0.51

Cause of death

   

0.09

Trauma

68(51.5%)

60(53.1%)

8(42.1%)

 

Cerebrovascular accident (CVA)

49(37.1%)

43(38.1%)

6(31.6%)

 

Other

15(11.4%)

10(8.8%)

5(26.3%)

 

Donor risk index

1.40 ± 0.27

1.40 ± 0.23

1.38 ± 0.22

0.37

Steatosis

   

0.38

 < 5%

38(28.8%)

30(26.5%)

8(42.1%)

 

5% ~ 15%

70(53.0%)

62(54.9%)

8(42.1%)

 

15% ~ 30%

24(18.2%)

21(18.6%)

3(15.8%)

 

Cold ischemia time

7.52 ± 2.01

7.45 ± 1.97

7.89 ± 2.28

0.64

  1. Tested by Student’s t-test or Pearson’s chi-squared (χ2) test; SD Standard Deviation; HBV Hepatitis B Virus; TBiL total bilirubin; Cr creatinine; INR International Normalized Ratio; HE hepatic encephalopathy; PT prothrombin time; Alb albumin; DBiL Direct Bilirubin; Hb hemoglobin; Plt platelet; WBC White Blood Cells; LYM lymphocyte count; NEUT neutrophil count