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Table 3 Associations between recurrence and clinicopathologic parameters

From: Risk stratification for predicting postoperative recurrence/metastasis of colorectal cancer by grade of venous invasion coupled with histological subtype

Histotype Parameter Odds ratio 95% CI Statistics p value
WMDA (n = 152) Age (≥ 65) 1.310 0.587–2.919 F 0.556
  Sex (male) 0.542 0.256–1.148 F 0.121
  Location (right) 1.405 0.639–3.091 F 0.413
  Depth of invasion N.C N.C C 0.000
  Venous invasion N.C N.C C 0.000
  Nodal metastasis (positive) 6.131 2.715–13.842 F 0.000
  pTNM Stage N.C N.C C 0.000
  Postoperative chemtherapy (done) 18.117 7.043–46.604 F 0.000
  Postoperative irradiation (done) N.C N.C F 0.001
PDA (n = 98) Age (≥ 65) 0.846 0.357–2.005 F 0.825
  Sex (male) 0.658 0.284–1.524 F 0.397
  Location (right) 1.179 0.503–2.761 F 0.830
  Depth of invasion N.C N.C C 0.058
  Venous invasion N.C N.C C 0.346
  Nodal metastasis (positive) 2.991 1.084–8.252 F 0.040
  pTNM Stage N.C N.C C 0.065
  Postoperative chemtherapy (done) 3.800 1.549–9.322 F 0.005
  Postoperative irradiation (done) N.C N.C F 0.123
MUA (n = 64) Age (≥ 65) 0.882 0.257–3.029 F 1.000
  Sex (male) 1.063 0.312–3.614 F 1.000
  Location (right) 1.841 0.568–5.970 F 0.382
  Depth of invasion N.C N.C C 0.320
  Venous invasion N.C N.C C 0.246
  Nodal metastasis (positive) 2.824 0.860–9.269 F 0.132
  pTNM Stage N.C N.C C 0.201
  Postoperative chemtherapy (done) 8.750 2.314–33.080 F 0.001
  Postoperative irradiation (done) 6.923 0.581–82.548 F 0.147
SRCC (n = 9) Age (≥ 65) 0.100 0.004–2.504 F 0.226
  Sex (male) 0.250 0.013–4.729 F 0.524
  Location (right) 2.000 0.112–35.807 F 1.000
  Depth of invasion N.C N.C C 1.000
  Venous invasion N.C N.C C 0.392
  Nodal metastasis (positive) N.C N.C F 0.464
  pTNM Stage N.C N.C C 0.526
  Postoperative chemtherapy (done) 10.000 0.399–250.419 F 0.183
  Postoperative irradiation (done) N.C N.C F 1.000
  1. In this study cohort, there were no cases of local recurrence throughout the histological subtypes. Therefore, recurrence means distant metastasis due to hematogenous/lymphatic metastasis or peritoneal dissemination
  2. WMDA well-to-moderately differentiated adenocarcinoma, PDA poorly differentiated adenocarcinoma, MUA mucinous adenocarcinoma, SRCC signet-ring cell carcinoma, pTNM pathologic tumor, node, metastasis, CI confidence interval, N.C not calculated, F Fisher's exact test, C chi-square test
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BMC Gastroenterology

ISSN: 1471-230X

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