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Table 3 Associations between recurrence and clinicopathologic parameters

From: Risk stratification for predicting postoperative recurrence/metastasis of colorectal cancer by grade of venous invasion coupled with histological subtype

Histotype

Parameter

Odds ratio

95% CI

Statistics

p value

WMDA (n = 152)

Age (≥ 65)

1.310

0.587–2.919

F

0.556

 

Sex (male)

0.542

0.256–1.148

F

0.121

 

Location (right)

1.405

0.639–3.091

F

0.413

 

Depth of invasion

N.C

N.C

C

0.000

 

Venous invasion

N.C

N.C

C

0.000

 

Nodal metastasis (positive)

6.131

2.715–13.842

F

0.000

 

pTNM Stage

N.C

N.C

C

0.000

 

Postoperative chemtherapy (done)

18.117

7.043–46.604

F

0.000

 

Postoperative irradiation (done)

N.C

N.C

F

0.001

PDA (n = 98)

Age (≥ 65)

0.846

0.357–2.005

F

0.825

 

Sex (male)

0.658

0.284–1.524

F

0.397

 

Location (right)

1.179

0.503–2.761

F

0.830

 

Depth of invasion

N.C

N.C

C

0.058

 

Venous invasion

N.C

N.C

C

0.346

 

Nodal metastasis (positive)

2.991

1.084–8.252

F

0.040

 

pTNM Stage

N.C

N.C

C

0.065

 

Postoperative chemtherapy (done)

3.800

1.549–9.322

F

0.005

 

Postoperative irradiation (done)

N.C

N.C

F

0.123

MUA (n = 64)

Age (≥ 65)

0.882

0.257–3.029

F

1.000

 

Sex (male)

1.063

0.312–3.614

F

1.000

 

Location (right)

1.841

0.568–5.970

F

0.382

 

Depth of invasion

N.C

N.C

C

0.320

 

Venous invasion

N.C

N.C

C

0.246

 

Nodal metastasis (positive)

2.824

0.860–9.269

F

0.132

 

pTNM Stage

N.C

N.C

C

0.201

 

Postoperative chemtherapy (done)

8.750

2.314–33.080

F

0.001

 

Postoperative irradiation (done)

6.923

0.581–82.548

F

0.147

SRCC (n = 9)

Age (≥ 65)

0.100

0.004–2.504

F

0.226

 

Sex (male)

0.250

0.013–4.729

F

0.524

 

Location (right)

2.000

0.112–35.807

F

1.000

 

Depth of invasion

N.C

N.C

C

1.000

 

Venous invasion

N.C

N.C

C

0.392

 

Nodal metastasis (positive)

N.C

N.C

F

0.464

 

pTNM Stage

N.C

N.C

C

0.526

 

Postoperative chemtherapy (done)

10.000

0.399–250.419

F

0.183

 

Postoperative irradiation (done)

N.C

N.C

F

1.000

  1. In this study cohort, there were no cases of local recurrence throughout the histological subtypes. Therefore, recurrence means distant metastasis due to hematogenous/lymphatic metastasis or peritoneal dissemination
  2. WMDA well-to-moderately differentiated adenocarcinoma, PDA poorly differentiated adenocarcinoma, MUA mucinous adenocarcinoma, SRCC signet-ring cell carcinoma, pTNM pathologic tumor, node, metastasis, CI confidence interval, N.C not calculated, F Fisher's exact test, C chi-square test