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Table 4 Comparisons of the performance indicators between two brands of pepsinogen testing using the logistic regression models

From: Brand interchangeability of pepsinogen tests in the real-world setting after eradication of Helicobacter pylori: a community-based study

Model* Odds ratio 95% CI
Positive predictive value for atrophic gastritis
 Model 1
  Test 1 vs. Test 2 1.00 0.42–2.38
 Model 2
  Test 1 vs. Test 2 1.12 0.40–3.12
  Age ≥ 50 vs. 30–49 years 3.68 0.67–20.16
  Male vs. female 1.11 0.34–3.61
Positive predictive value for intestinal metaplasia
 Model 1
  Test 1 vs. Test 2 1.16 0.54–2.48
 Model 2
  Test 1 vs. Test 2 1.75 0.65–4.67
  Age ≥ 50 vs. 30–49 years 5.97 1.12–31.77
  Male vs. female 2.84 0.94–8.55
Detection rate for atrophic gastritis
 Model 1
  Test 1 vs. Test 2 1.00 0.45–2.23
 Model 2
  Test 1 vs. Test 2 1.00 0.45–2.24
  Age ≥ 50 vs. 30–49 years 5.61 1.30–24.15
  Male vs. female 1.37 0.58–3.25
Detection rate for intestinal metaplasia
 Model 1
  Test 1 vs. Test 2 1.13 0.57–2.21
 Model 2
  Test 1 vs. Test 2 1.20 0.60–2.40
  Age ≥ 50 vs. 30–49 years 8.91 2.12–37.51
  Male vs. female 2.23 1.01–4.96
  1. CI, confidence interval; Test 1, GastroPanel (Biohit HealthCare, Helsinki, Finland); Test 2, LZ-Test (Eiken Chemical Co., Ltd, Tokyo, Japan)
  2. *Model 1: the univariate logistic regression model; model 2: the multivariate logistic regression model also adjusted for body mass index, social habits, and the medical histories, in addition to the age and sex
  3. P < 0.05