Variables | Patient (n = 370) | OS | |||||
---|---|---|---|---|---|---|---|
No. of events | MST (days) | HR (95% CI) | P | Adjusted HR (95% CI) | Adjusted Pa | ||
CDK1 | Â | Â | Â | Â | Â | Â | Â |
 LOW | 185 | 53 | 2131 | 1 |  | 1 |  |
 HIGH | 185 | 77 | 1149 | 1.796 (1.265–2.551) | 0.001 | 1.541 (1.048–2.266) | 0.028 |
CDK2 | Â | Â | Â | Â | Â | Â | Â |
 LOW | 185 | 61 | 2116 | 1 |  | 1 |  |
 HIGH | 185 | 69 | 1490 | 1.450 (1.025–2.051) | 0.036 | 1.305 (0.896–1.900) | 0.165 |
CDK3 | Â | Â | Â | Â | Â | Â | Â |
 LOW | 185 | 65 | 13,786 | 1 |  | 1 |  |
 HIGH | 185 | 65 | 1852 | 0.775 (0.534–1.067) | 0.111 | 0.934 (0.640–1.363) | 0.723 |
CK4 | Â | Â | Â | Â | Â | Â | Â |
 LOW | 185 | 54 | 2456 | 1 |  | 1 |  |
 HIGH | 185 | 76 | 1229 | 1.779 (1.253–2.526) | 0.001 | 1.721 (1.179–2.513) | 0.005 |
CDK6 | Â | Â | Â | Â | Â | Â | Â |
 LOW | 185 | 66 | 1624 | 1 |  | 1 |  |
 HIGH | 185 | 64 | 1852 | 1.042 (0.738–1.471) | 0.815 | 1.068 (0.733–1.554) | 0.733 |